Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Testing Earlier for Gestational Diabetes a Smarter Way to Screen Pregnant Women

23.08.2002


Testing pregnant women for gestational diabetes at 16-weeks of pregnancy is a more efficient way to screen for the disease than the current method of screening women during their third trimester, said Gerard Nahum, M.D., an associate clinical professor at Duke University Medical Center’s department of obstetrics and gynecology.



The earlier tests, Nahum said, allow women at highest risk for gestational diabetes to be identified and treated earlier, possibly heading off complications in both mother and baby. He is lead author of a study on the findings that appears in the August 2002 issue of the Journal of Reproductive Medicine.

Obstetricians have usually screened women in their third trimester because most doctors believe that screening later in pregnancy is more accurate. However, he said, “Screening at 16 weeks is a better predictor of gestational diabetes. It’s more sensitive than screening later, and allows us to focus earlier on women who are at greatest risk. It’s also a more practical screening technique because blood samples drawn during early pregnancy for other tests can also be used for this purpose.”


Nahum and colleagues from the University of Hawaii School of Medicine and California State University studied 255 pregnant women who visited a private obstetrics practice in Honolulu.

All of the women were given a glucose screening test between 14 and 18 weeks of pregnancy. At initial screening, 14 of the 255 women had blood plasma glucose levels higher than 135 milligrams of glucose per deciliter of blood (mg/dL) and were sent for additional testing to confirm a gestational diabetes diagnosis.

The remaining 241 women were screened again at between 24 and 32 weeks. At either point, if women tested higher than 135 mg/dL, they were sent for additional formal glucose tolerance testing.

“Women who had a 16-week glucose screening test result of less than 110 mg/dL had a 99.4 percent chance of not developing gestational diabetes,” said Nahum. “None of the women who had a result of less than 104 mg/dL developed gestational diabetes. This gives us a cutoff point. Women who test in this range at 16 weeks are almost guaranteed not to develop gestational diabetes.”

Nahum said that for women who fall in the intermediate range (111 mg/dL to 134 mg/dL) at 16 weeks, a repeat glucose screening test should be given at 28 weeks to assess whether the woman should be sent for more in-depth testing.

While it is a natural assumption to say that earlier screenings should lead to better outcomes for mother and baby, Nahum said more studies are needed to confirm that.
“We don’t know how earlier diagnosis of gestational diabetes will impact maternal-fetal outcomes because we didn’t examine that in this study, but that is certainly something to focus on in future research,” he said.

Gestational diabetes occurs in 2 percent to 7 percent of all pregnancies in the United States. It develops when a pregnant woman is not able to produce enough insulin to keep her blood sugar, also known as glucose, within a normal range that is safe for her and her developing baby.

Complications from gestational diabetes include above-average weight gain for the baby that can result in injury to the nerves in the baby’s neck from a difficult delivery, an increased risk of newborn fractures, a higher likelihood of fetal distress and possible hypoglycemia, jaundice or breathing problems in the baby.

Changes in diet and exercise are usually enough to help keep blood sugar levels within the normal range, but in some cases insulin injections are needed. Most women who develop diabetes during pregnancy go back to having normal glucose tolerance after the birth of the baby; however, these women may be at greater risk for adult onset diabetes mellitus later in life.

Co-authors include Stephen B. Wilson, M.D., University of Hawaii School of Medicine; and Harold Stanislaw, Ph.D., California State University.

Amy Austell | EurekAlert!
Further information:
http://dukemednews.org/
http://hawaiimed.hawaii.edu/
http://www.csustan.edu/

More articles from Health and Medicine:

nachricht Researchers release the brakes on the immune system
18.10.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Terahertz spectroscopy goes nano

20.10.2017 | Information Technology

Strange but true: Turning a material upside down can sometimes make it softer

20.10.2017 | Materials Sciences

NRL clarifies valley polarization for electronic and optoelectronic technologies

20.10.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>