A sort of biochemical scaffold for a compound that enables blood pressure to be low, heart bypass grafts to remain open and nerves to communicate has been identified by Medical College of Georgia researchers.
Dr. Richard C. Venema (left) and Dr. John D. Catravas have received American Heart Association and National Institutes of Health funding to study a biochemical scaffold they have discovered that helps keep blood pressure low and heart bypass grafts open.
A process called co-localization looks for the presence of two key proteins in the scaffold the researchers found; the antibody for heat shock protein 90 is labeled green and the one for sGC is labeled red. The yellow images show the proteins are found together in the living endothelial and smooth muscle cell. The left side shows the proteins in the endothelial cell and the right shows a smooth muscle cell.
Researchers say identifying the framework for how these and other very positive health benefits occur should help them find ways to augment the benefits and identify new treatments for cardiovascular disease, which may result when the support structure falls apart.
"Its a whole new ball game," Dr. John D. Catravas, director of the Vascular Biology Center, said of the findings which contradict previous understanding of how the compound, cyclic GMP, which also helps keep blood vessels open and enables penile erection, is ultimately produced.
Toni Baker | EurekAlert!
Tracking movement of immune cells identifies key first steps in inflammatory arthritis
23.01.2017 | Massachusetts General Hospital
Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign
For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.
According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
23.01.2017 | Health and Medicine
23.01.2017 | Physics and Astronomy
23.01.2017 | Process Engineering