Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Intensive care treatment may be bad for your health

12.08.2002


Two articles in the latest issue of Critical Care reveal how intensive care therapy may be beneficial in the short but not in the long term. Being treated in intensive care units may help critically ill patients survive but the quality of life - if they survive - is often severely impaired. It is unclear whether this impairment is a complication of the illness or a complication of therapy.



Many intensive care doctors believe the battle has been won once a patient leaves the intensive care unit, however Gordon Rubenfeld from the University of Washington in Seattle suggests that it is important to focus intensive care treatment on improving the long-term health of those who survive. Rubenfeld shows that doctors may face a conflict in deciding on treatments that are best at saving lives and those that give the best quality of life to those patients who survive. He stresses that more research is needed to make these decisions with confidence.

An example of research into how well or badly patients fare after they have left the intensive care unit is the study by Dale Rublee and colleagues. It examines the long-term effects of treating patients with sepsis with the drug antithrombin III. Antithrombin III affects the blood`s clotting mechanism and is a potential treatment for sepsis, a critical condition characterised by a combination of problems with the clotting mechanism and an inflammation throughout the body, which can lead to multiple organ failure and death.


The results of this study suggest that treatment with antithrombin III neither improves nor diminishes patients` chances of survival but it does leave patients with an improved quality of life 90 days after treatment. By focusing on the long-term effects of treatment Rublee and colleagues may have identified a treatment that will help improve the quality of patients` lives if they survive critical illness.

Quality of life was measured by looking at a range of factors such as the patients` mobility, their level of physical activity and their ability to communicate effectively. The study showed that improvements in social and psychological functioning were most marked in patients treated with antithrombin III.

Reducing the long-term impairment in health associated with critical illness represents a new challenge in medicine and it is hoped that clinical research will begin to focus on these issues.

###

The research article by Dale Rublee and colleagues is freely available in Critical Care, a journal published by BioMed Central, simply visit: http://ccforum.com/inpress/cc-6-4-rublee

The accompanying commentary by Gordon Rubenfeld can be found in the same issue of Critical Care, for access to this article visit: http://ccforum.com/info/media/press-releases/rubenfeld.pdf

Any articles published using the material featured in these articles should reference Critical Care, a journal published by BioMed Central.

Please contact Gordon Fletcher for further information, email - gordon@biomedcentral.com, phone - +44 (0) 20 7323 0323

Critical Care is a journal published by BioMed Central http://www.biomedcentral.com, an independent online publishing house committed to providing immediate free access to the peer-reviewed biological and medical research it publishes. This commitment is based on the view that open access to research is essential to the rapid and efficient communication of science. In addition to open-access original research, BioMed Central also publishes reviews, abstracts and subscription-based content.

Gordon Fletcher | alfa
Further information:
http://ccforum.com/inpress/cc-6-4-rublee
http://ccforum.com/info/media/press-releases/rubenfeld.pdf

More articles from Health and Medicine:

nachricht New malaria analysis method reveals disease severity in minutes
14.08.2017 | University of British Columbia

nachricht New type of blood cells work as indicators of autoimmunity
14.08.2017 | Instituto de Medicina Molecular

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

A Map of the Cell’s Power Station

18.08.2017 | Life Sciences

Engineering team images tiny quasicrystals as they form

18.08.2017 | Physics and Astronomy

Researchers printed graphene-like materials with inkjet

18.08.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>