According to the World Health Organization, Tuberculosis (Mycobacterium tuberculosis or TB) will kill two million people this year, with the projected number of new infections over the next twenty years reaching a billion. A rapidly moving, constantly mutating disease, TB’s effects are made worse by its ability to quickly react to new drug treatments, becoming resistant to antibiotics. Searching for a way to improve treatment, a group of researchers from the University of Tennessee developed a model to determine the most effective way of managing the bacteria’s resistance.
Drug cycling is one of many drug use policies that can be applied to treat illness and manage the resistance of viruses and bacteria. Depending on when a person becomes infected, they are placed in a group to receive a particular drug treatment. Groups infected later or earlier are treated with different drugs. Mathematical model results support that cycling is potentially useful as a tool for controlling the resistance of pathogens such as Tuberculosis.
“Tuberculosis resistance is not just an issue to minimize locally; it’s a global concern,” says Scott Duke-Sylvester, one of the researchers who will present the group’s work at the Modeling session during the Ecological Society of America’s Annual Meeting.
Annie Drinkard | EurekAlert!
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Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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24.03.2017 | Physics and Astronomy