Professor Jennifer Kirkham, Research Director of Leeds Dental Institute explains: “The laboratory is looking to find safe new ways to control plaque which do not rely on toothpaste.
We see patients in the clinic who are not able to brush effectively – the shape of the mouth may not allow sufficient access, the patient could be disabled or just not a proficient brusher.
“One of the new treatments makes use of a readily available compound in an innovative way to control plaque formation, using photo dynamic therapy (PDT). The patient uses a mouth wash containing an anti-bacterial agent which is activated by bright light and results in plaque destruction. This is trialled in the clinic and patient feedback helps researchers identify where further modifications are needed.
“The principle of working from bench to clinic and back to bench will see a circle of constant improvements to oral health and it is this partnership with patients which ensures research has an impact. “
Another research project could transform the approach to filling teeth forever. Professor Kirkham explains.
“Tooth decay begins when acid produced by the bacteria in plaque dissolves the tooth minerals, resulting in microscopic pores in the teeth. We have developed a method for “Filling without Drilling” that uses a low viscosity protein–based fluid which is painted onto the teeth where it infiltrates into the pores. Once inside the pores, the fluid solidifies, to become a gel which then attracts calcium to rebuild the tooth mineral, bringing about a natural repair, without the pain or discomfort usually associated with a traditional drilling procedure. “
A £1.5 million investment by the University of Leeds is set to bring the new Dental Clinic and Translational Research Unit to the forefront of global research and development in oral health by linking the laboratory activity directly to the needs of patients treated in the clinic.
The flagship centre for world class dental research and clinical practice, the first of its kind in the UK, opens at the Leeds Dental Institute in January 2009.
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Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
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Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
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Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
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Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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