Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Low-sodium advice for asthmatics should be taken with a pinch of salt

16.07.2008
Following a low-sodium diet does not appear to have any appreciable impact on asthma control, according to new research.

Contrary to past studies — which have suggested a link between low-sodium diets and improved asthma control — a new study by researchers at The University of Nottingham found no evidence that cutting back on salt helps patients with their symptoms.

Dr Zara Pogson, clinical research fellow at The University of Nottingham, said: “Despite the clear benefit of a low-sodium diet on cardiovascular risk factors, there is no therapeutic benefit in the use of a low-sodium diet…on asthma control in our study population.”

The results of the randomised, double-blind, placebo-controlled trial were published in the second issue for July of the American Journal of Respiratory and Critical Care Medicine by the American Thoracic Society.

Nearly 200 subjects completed the study which compared the effect of changes in bronchial reactivity — a measure of asthma activity — on asthma patients who followed a strict low-sodium diet. Each subject either received sodium supplements to approximate normal sodium intake of 80 millimoles per litre (mmol) a day, or a placebo, for six weeks.

Dr Pogson and colleagues hypothesized that the subjects on the low sodium intake would show improved clinical control of asthma symptoms based on a test of asthma activity, measures of lung function, asthma symptoms and use of asthma medication. Contrary to their hypothesis, however, they detected no differences in any measures of asthma between the groups.

“We observed no difference in the outcome measures related to asthma activity in adults with asthma and bronchial reactivity who adopted a low-sodium diet for six weeks compared with those who did not, despite a final difference in daily sodium excretion of 50 mmol,” wrote Dr Pogson.

While past studies have suggested a link between low-sodium diets and improved asthma control, none were as large or tightly controlled as this study, suggesting that their findings may have been artifacts of study design rather than reflective of a true therapeutic benefit.

“We were disappointed that a simple measure, such as a decrease in sodium intake, does not result in improvements in asthma control,” said Dr Pogson. “We therefore cannot advise people with asthma to alter their sodium intake to improve control of their asthma, despite the fact that a low-sodium diet improves cardiovascular risk factors. This study suggests that further dietary research in asthma should be directed to factors other than sodium.”

According to Asthma UK, 5.2 million people in the UK have asthma — and 50 per cent of these people have severe asthma symptoms that have a major impact on their daily lives.

Emma Thorne | alfa
Further information:
http://www.nottingham.ac.uk
http://communications.nottingham.ac.uk/News/Article/Low-sodium_advice_for_asthmatics_should_be_taken_with_a_pinch_of_salt.html

More articles from Health and Medicine:

nachricht Laser activated gold pyramids could deliver drugs, DNA into cells without harm
24.03.2017 | Harvard John A. Paulson School of Engineering and Applied Sciences

nachricht What does congenital Zika syndrome look like?
24.03.2017 | University of California - San Diego

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

Im Focus: Researchers Imitate Molecular Crowding in Cells

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.

Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Argon is not the 'dope' for metallic hydrogen

24.03.2017 | Materials Sciences

Astronomers find unexpected, dust-obscured star formation in distant galaxy

24.03.2017 | Physics and Astronomy

Gravitational wave kicks monster black hole out of galactic core

24.03.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>