Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

6 of every 100 patients die in hospital due to adverse drug reaction

08.07.2008
Six of every 100 patients who die in hospital do so as a consequence of an adverse drug reaction or, in other words, a fatal reaction to medicines.

Those are the conclusions of a research carried out at the Department of Medicine of the University of Granada, in collaboration with the Clinical Hospital San Cecilio of Granada, by Alfredo José Pardo Cabello and directed by Professors Emilio Puche Cañas (Department of Pharmacology) and Francisco Javier Gómez Jiménez (Department of Medicine).

A adverse drug reaction to medicines (ADR) has been defined as any harmful and unwanted effect of a drug, at doses used for prophylaxis, diagnose or treatment. Their repercussion is usually minimal, but sometimes, they can be serious and they can even endanger the patient’s life.

In order to carry out this work, they analysed the clinical case history of 289 patients older than 18 who died in hospital in 2004, revising their history, the drugs they were administered, as well as data about the treatment and the death certificate. Their analysis concluded that the most frequent ADR are the digestive haemorrhages followed by intra-cranial haemorrhages and cardiac arrhythmias.

Most frequent drugs
The work carried out at the UGR has revealed that the drugs which provoked an ADR usually were AINE (medicines with a strong anti-inflammatory, analgesic and antipyretic effect) as well as platelet anti-aggregants, such as acetylsalicylic acid, two types of drugs frequently used in the daily medical practice.

Pardo Cabello has also proved the convenience of avoiding the mixing of gastro-damaging drugs such as NSAIDs, anti-aggregants and corticoids, as 53% of the deaths caused by ADR analyzed in this study had received a mixing of such medicines.

The author of this work has highlighted that, in the light of the obtained results, it is necessary to create a better awareness among the sanitary staff about adverse drug reactions and to be on the alert in the face of the slightest symptom. The research work carried out at the UGR is a completely pioneer in Spain and the results obtained coincide with those of other similar studies carried out in USA and Finland.

Reference
Alfredo José Pardo Cabello. Department of Medicine of the University of Granada.
Tel: +34 958244054.
E-mail: apardoc05@yahoo.es

Antonio Marín Ruiz | alfa
Further information:
http://www.ugr.es
http://prensa.ugr.es/prensa/research/verNota/prensa.php?nota=529

More articles from Health and Medicine:

nachricht Spanish scientists create a 3-D bioprinter to print human skin
24.01.2017 | Carlos III University of Madrid

nachricht Tracking movement of immune cells identifies key first steps in inflammatory arthritis
23.01.2017 | Massachusetts General Hospital

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Scientists spin artificial silk from whey protein

X-ray study throws light on key process for production

A Swedish-German team of researchers has cleared up a key process for the artificial production of silk. With the help of the intense X-rays from DESY's...

Im Focus: Quantum optical sensor for the first time tested in space – with a laser system from Berlin

For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.

According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Breaking the optical bandwidth record of stable pulsed lasers

24.01.2017 | Physics and Astronomy

Choreographing the microRNA-target dance

24.01.2017 | Life Sciences

Spanish scientists create a 3-D bioprinter to print human skin

24.01.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>