Michael Reid, chair of UK’s Department of Physiology and a founding member of the National Space Biomedical Research Institute, is researching the value of N-acetylcysteine (NAC) to limit the effect of free radicals made by muscle during heavy exercise.
His research, funded by NASA, has particular value for astronauts who work in bulky space suits. "Astronauts report that six to eight hours of extra-vehicular activity is as exhausting as running a marathon. The muscle groups most affected are the hands and arms," he said.NAC was developed in the late 1950s and has become a frontline drug in protecting the liver against drug overdose by scavenging free radicals.
"Free radicals also contribute to muscle fatigue," Reid said. His research has found that NAC "will improve endurance. Now we’re trying to determine the right dose and formulation" for space-travel purposes, he said.
Reid and his team also are concerned about muscle wasting that occurs during deep-space exploration, such as long-term stays on the moon and extended flights to Mars.
Astronaut Reisman knows first-hand the wasting effects of extended periods in low- or no-gravity situations, having just returned to earth from three months in the International Space Station.
"We’ve seen the muscles that astronauts use to stand and walk begin to waste away after a few weeks in Earth orbit. So we know nine months of travel to Mars poses a real risk," Reid said.
"At UK, we’re seeking nutritional or drug-based therapies to help the astronauts maintain muscle mass and strength," he said.
The research has potential ripples beyond space travel.
"If these nutritional strategies help astronauts, they’ll also help the elderly who suffer broken hips. We’re also working with heart-failure patients to determine possible benefits of NAC for them," Reid said.
The research also could benefit cancer patients who undergo chemotherapy, which has been found to have a direct impact on muscles, Reid said.
In striving to become a Top 20 public research institution, the University of Kentucky is a catalyst for a new Commonwealth – a Kentucky that is healthier, better educated, and positioned to compete in a global and changing economy. For more information about UK’s efforts to become a Top 20 university, please go to http://www.uky.edu/OPBPA/Top20.html
Dan Adkins | newswise
'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers
16.02.2018 | National University of Science and Technology MISIS
New process allows tailor-made malaria research
16.02.2018 | Eberhard Karls Universität Tübingen
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
Let’s say the armrest is broken in your vintage car. As things stand, you would need a lot of luck and persistence to find the right spare part. But in the world of Industrie 4.0 and production with batch sizes of one, you can simply scan the armrest and print it out. This is made possible by the first ever 3D scanner capable of working autonomously and in real time. The autonomous scanning system will be on display at the Hannover Messe Preview on February 6 and at the Hannover Messe proper from April 23 to 27, 2018 (Hall 6, Booth A30).
Part of the charm of vintage cars is that they stopped making them long ago, so it is special when you do see one out on the roads. If something breaks or...
15.02.2018 | Event News
13.02.2018 | Event News
12.02.2018 | Event News
16.02.2018 | Information Technology
16.02.2018 | Health and Medicine
16.02.2018 | Physics and Astronomy