Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Atishoo! From babies with colds to bird flu - new centre to tackle respiratory infections

02.06.2008
Think that colds and flu are easy to catch, hard to avoid and impossible to treat? That nobody ever dies of a cold? That's all wrong, say the medics and scientists at a new research centre which launches today (Monday 2 June).

Research into respiratory infections is an urgent priority, they argue. Colds can be a very serious problem for the elderly, babies, and patients with lung disease. History suggests a major flu pandemic is overdue and drug resistant tuberculosis and other 'superbugs' are on the rise.

The new Centre for Respiratory Infection at Imperial College London aims to tackle these issues. It is funded by a £3.4 million award from the Wellcome Trust and will bring together more than 200 scientists to work on a range of problems - how common cold viruses cause disease and affect long-term health, how to make better vaccines to prevent lung infections, and how to diagnose TB more accurately. The centre will also be ready to spring into action if there is a new outbreak of pandemic flu such as a mutated form of bird flu, or SARS.

Professor Peter Openshaw, the Director of the new centre from the National Heart and Lung Institute at Imperial College London, said: "Respiratory disease has never been as well funded as it deserves to be, considering the impact it has on health. Respiratory infections are at the root of many of the diseases that we treat every day. This new initiative is a great opportunity to get something done. We have a lot of very talented groups working on different aspects of lung infections, and bringing them together with solid shared support will help them work on common goals, to the great benefit of patients".

Examples of problems which the centre will tackle include:

* How to quickly bring a flu pandemic under control

Researchers from the new centre are establishing a clinical team that will bring doctors and researchers together to bring a future flu pandemic under control quickly and effectively.

If an outbreak of pandemic flu strikes, doctors will only be able to get the best treatments to patients if they can first analyse the flu strain and find out which therapies are going to work. However, planning and setting up the necessary trials to obtain this information would usually take months.

The new centre will put plans in place in advance, so that researchers can get to work before the epidemic spreads too widely and so that doctors working on the ground are fully prepared.

The researchers will be working closely with colleagues at Imperial College Healthcare NHS Trust and the MRC Centre for Outbreak Analysis and Modelling at Imperial College London, and with other scientists and government agencies across the world.

Professor Openshaw explained: "We can only move fast to bring an epidemic under control if we have staff ready and plans already in place. To plan at the stage when patients start coming in through casualty will be impossible."

* Why the common cold in babies can cause long term health problems

The respiratory syncytial virus (RSV), which causes colds in adults, is the main single cause of hospitalisation in babies under a year of age. It causes most cases of viral bronchiolitis, an infection of the small airways of the lung which leads to breathing problems and which results about 1 in every 40 babies affected being admitted to hospital. Around 40 percent of infants who experience bronchiolitis as a result of RSV infection are affected by recurring wheeze and asthma in childhood.

The researchers will investigate why some babies get severe disease, while the majority recover with ease. Imperial College researchers have already made many important discoveries about RSV, including a study in 2004 which revealed that RSV can 'hit and hide', surviving in the body for many months or years. They are now investigating whether recurrent wheezing in children could be caused by the virus hiding in the lung.

Laura Gallagher | alfa
Further information:
http://www.wellcome.ac.uk
http://www.imperial.ac.uk

More articles from Health and Medicine:

nachricht Cholesterol-lowering drugs may fight infectious disease
22.08.2017 | Duke University

nachricht Once invincible superbug squashed by 'superteam' of antibiotics
22.08.2017 | University at Buffalo

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

Cholesterol-lowering drugs may fight infectious disease

22.08.2017 | Health and Medicine

Meter-sized single-crystal graphene growth becomes possible

22.08.2017 | Materials Sciences

Repairing damaged hearts with self-healing heart cells

22.08.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>