Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Prostate cancer screening programme leads to bigger fall in death rates than surrounding areas

22.04.2008
The expected number of deaths from prostate cancer more than halved in the Tyrol after a programme was introduced to improve early detection and treatment of the disease, according to research published in April issue of the urology journal BJU International.

Nearly 87 per cent of eligible men have been tested at least once since the programme was introduced in 1988. By 2005 cancer deaths had fallen by 54 per cent, compared with 29 per cent for the rest of Austria, which hadn’t benefited from the programme.

There is no evidence that trends in the Tyrol and the rest of Austria were significantly different before free testing was introduced.

“Prostate specific antigen (PSA) testing was introduced to the Tyrol in 1988 and since 1993 it has been freely available to all men aged from 45 to 75 and to men under 40 with a family history of the disease” explains lead author Professor Georg Bartsch from the University of Innsbruck, one of the international team of medical experts that makes up the Tyrol Prostate Cancer Screening Group.

“Our findings suggest that the combination of free PSA testing and free treatment for any resulting prostate cancer can lead to significant reductions in death rates. This free treatment normally involved surgical removal of the prostate.

“What was interesting about this study was that so many men came forward for testing after the programme was widely advertised in the print and broadcast media. People living in the Tyrol – one of the nine Federal states that make up Austria – tend to enjoy close proximity to health facilities and be very receptive to preventative medical programmes.”

By 2005, just under 87 per cent of men aged between 45 and 75 living in the region had undergone a PSA test.

“Our study clearly shows that deaths from prostate cancer have declined much more quickly in the Tyrol since 1988, when this programme was introduced, compared with the rest of Austria.

“Before the programme was introduced, prostate cancer death rates in the Tyrol were similar to the rest of the country, but after the programme was launched the death rate in the Tyrol started falling by an average of 7.3 per cent a year, more than twice the 3.2 per cent observed in the rest of Austria.”

The findings also have important implications for age-related prostate cancer deaths, say the researchers, especially as the number of older men is steadily increasing.

“Deaths from prostate cancer in the 80 plus age group have been increasing across Austria, but there has been no evidence of this happening in the Tyrol” says co-author Professor Boyle from the International Agency for Research on Cancer.

“This indicates that the screening programme in the Tyrol is picking up cases of prostate cancer at an earlier stage of the disease, when it can be treated more effectively. This early treatment reduces the risk of the disease coming back later in life and killing the patient when they are older.”

The authors conclude that the introduction of free screening has made an important contribution to reducing prostate cancer death rates in the Tyrol, a region where treatment is freely available to all patients with the disease.

But they acknowledge that there is still controversy surrounding some aspects of screening for prostate cancer that need to be resolved.

These include the effectiveness of PSA testing in all cases, whether aggressive treatment alters the outcome in men with advanced stages of the disease and whether testing and treatment seriously impinge quality of life.

“Our study shows that when widespread PSA testing was introduced to the Tyrol, and people with the disease received free treatment to cure their prostate cancer, the fall in death rates was significantly higher than in the rest of Austria” says Professor Boyle.

“This reduction in death rates is most probably due to the fact that cases of prostate cancer were detected at an earlier stage, when treatment for this disease tends to be more effective.

“However it is important to remember that screening is only the first step in the optimal management of patients with prostate cancer.”

Annette Whibley | alfa
Further information:
http://www.bjui.org

More articles from Health and Medicine:

nachricht Cholesterol-lowering drugs may fight infectious disease
22.08.2017 | Duke University

nachricht Once invincible superbug squashed by 'superteam' of antibiotics
22.08.2017 | University at Buffalo

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

What the world's tiniest 'monster truck' reveals

23.08.2017 | Life Sciences

Treating arthritis with algae

23.08.2017 | Life Sciences

Witnessing turbulent motion in the atmosphere of a distant star

23.08.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>