Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New imaging technology promises better breast cancer detection in early stages

25.06.2002


Scientists at the Research & Education Institute at Harbor-UCLA Medical Center (REI) are developing a new breast imaging diagnostic tool which will afford clinicians greater opportunities for detecting early stage breast cancers with greater certainty and help patients avoid biopsy in some cases. This detection method identifies breast lesions utilizing a radiopharmaceutical diagnostic imaging technology known as Tc-99 Sestamibi (MIBI) scintimammography. The procedure is based on a radioactive isotope being injected into a vein in the arm. Once absorbed into the body, the isotope can be seen by a group of special detectors, called gamma cameras, "marking" certain biological processes to locate a tumor.



Iraj Khalkhali, MD, principal investigator at REI, believes that the number of false negative (i.e., missed tumors) readings could be reduced if the limitations of contemporary gamma cameras were overcome. In one of his studies, Dr. Khalkhali found that three out of four false negatives were in the middle part of the breast and out of range of close camera contact. Dr. Khalkhali is currently pursuing research on improving scintimammography image quality through the design and development of a compact, thin gamma camera that affords easier access to all nodes and potential breast lesion sites.

"Access to breast lesions in the internal quadrants is especially important because these tumors may disseminate toward the internal mammary chain even when no axillary node is invaded. Easy access to all nodes and potential breast lesion sites will improve image quality and can be expected to improve the diagnostic accuracy of scintimammography, " said Dr. Khalkhali. "Although mammography is currently the standard early diagnostic screening tool, scintimammography has proven to be a highly effective adjunct in identifying lesions missed by mammography – particularly in women with dense breast tissue, low suspicion lesions on mammograms, pre-menstrual women with lumps in their breasts and women with locally advanced breast cancer," he added.



Dr. Khalkhali has long been recognized as an innovator and pioneer in advancing breast imaging techniques. He is founder and first president of the Nuclear Radiology Section of the Los Angeles Radiological Society. A graduate of the University of Tehran School of Medicine, he served his residency in diagnostic radiology at the Albert Einstein College of Medicine, Bronx, NY, and the University of California, Davis. He is the recipient of the County of Los Angeles Commendation for Excellence in Women’s Health for 2001, winner of the Outstanding and First Place Resident Research Award 1997 for a paper presented on "Detection of Axillary Lymph Node Metastasis of Breast Carcinoma with Technetium 99m Sestamibi Scintimammography", and holds a patent for the scintigraphy guided stereotaxic localization technique of breast tumors.

The Research & Education Institute at Harbor-UCLA Medical Center, located on the campus of Harbor-UCLA Medical Center in Torrance, California, is a leading independent, not-for-profit biomedical research institute with an international reputation for scientific discovery, the training of physician-scientists and the provision of community service programs. It is an affiliate of both the David Geffen School of Medicine at UCLA and the Harbor-UCLA Medical Center and has an annual budget of $58 million. The Institute traces its roots back to 1952, when researchers and physicians joined forces with the UCLA School of Medicine on the campus of what was then known as Harbor General Hospital to conduct a handful of research studies. Today, more than 1,000 research projects and clinical trials are being conducted at REI, advancing scientific understanding in order to improve medical outcomes and promote innovation in such areas as autoimmune disorders, cancer, cardiovascular disease, developmental disorders and other pediatric health problems, diabetes, infectious disease, inherited disorders, male contraception, vaccine evaluation and research, and various aspects of women’s health.


Barbara Kerr | EurekAlert!

More articles from Health and Medicine:

nachricht How cancer metastasis happens: Researchers reveal a key mechanism
19.01.2018 | Weill Cornell Medicine

nachricht Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Let the good tubes roll

19.01.2018 | Materials Sciences

How cancer metastasis happens: Researchers reveal a key mechanism

19.01.2018 | Health and Medicine

Meteoritic stardust unlocks timing of supernova dust formation

19.01.2018 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>