Scientists at the Research & Education Institute at Harbor-UCLA Medical Center (REI) are developing a new breast imaging diagnostic tool which will afford clinicians greater opportunities for detecting early stage breast cancers with greater certainty and help patients avoid biopsy in some cases. This detection method identifies breast lesions utilizing a radiopharmaceutical diagnostic imaging technology known as Tc-99 Sestamibi (MIBI) scintimammography. The procedure is based on a radioactive isotope being injected into a vein in the arm. Once absorbed into the body, the isotope can be seen by a group of special detectors, called gamma cameras, "marking" certain biological processes to locate a tumor.
Iraj Khalkhali, MD, principal investigator at REI, believes that the number of false negative (i.e., missed tumors) readings could be reduced if the limitations of contemporary gamma cameras were overcome. In one of his studies, Dr. Khalkhali found that three out of four false negatives were in the middle part of the breast and out of range of close camera contact. Dr. Khalkhali is currently pursuing research on improving scintimammography image quality through the design and development of a compact, thin gamma camera that affords easier access to all nodes and potential breast lesion sites.
"Access to breast lesions in the internal quadrants is especially important because these tumors may disseminate toward the internal mammary chain even when no axillary node is invaded. Easy access to all nodes and potential breast lesion sites will improve image quality and can be expected to improve the diagnostic accuracy of scintimammography, " said Dr. Khalkhali. "Although mammography is currently the standard early diagnostic screening tool, scintimammography has proven to be a highly effective adjunct in identifying lesions missed by mammography – particularly in women with dense breast tissue, low suspicion lesions on mammograms, pre-menstrual women with lumps in their breasts and women with locally advanced breast cancer," he added.
Barbara Kerr | EurekAlert!
Penn vet research identifies new target for taming Ebola
12.01.2017 | University of Pennsylvania
The strange double life of Dab2
10.01.2017 | University of Miami Miller School of Medicine
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).
Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...
Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.
The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...
UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration
"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...
Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.
Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...
10.01.2017 | Event News
09.01.2017 | Event News
05.01.2017 | Event News
16.01.2017 | Power and Electrical Engineering
16.01.2017 | Information Technology
16.01.2017 | Power and Electrical Engineering