Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Grants of over £500,000 for Queen’s to investigate blindness

11.03.2008
Queen’s Centre for Vision Science (CVS) has been boosted by grants of over £500,000 from three charities to investigate the two leading causes of blindness in the UK.

Recognised as a centre of excellence for ophthalmic research, its researchers, led by director Professor Alan Stitt, will carry out studies of sight-threatening conditions affecting diabetics and the elderly over the next three years. The team, part of the School of Biomedical Sciences, is based in the Royal Victoria Hospital.

The largest grant has come from the New-York based Juvenile Diabetes Research Foundation which has awarded Professor Stitt over £250,000 for research into diabetic retinopathy – a disease that causes about 40 per cent of new adult blindness in the UK.

After 20 years, almost everyone with type 1 diabetes will develop some form of retinopathy.

Sight can be saved by laser therapy if the condition is detected early enough, but the cost of treating just one person is around £237,000. Professor Stitt and his team will investigate the nature of chemical modifications in the retina and their role in the condition. They will study the effects that oxygen deficiency and high blood glucose can have on the build up of glucose residue in blood vessels in the retina.

Professor Stitt has also been awarded two other grants to research into age-related macular degeneration (AMD) – the leading cause of sight loss in people over 50 in the western world.

Around two million people in UK are affected, with numbers set to rise dramatically as our population ages.

Over £170,000 has been granted by the charity Action Medical Research to try to find important information about the molecular and cellular processes that damage the retina, and cause vision loss in AMD.

The charity Fight for Sight has given over £90,000 for the team to understand the role of chemical modifications and the way they interact with a receptor in causing the condition. It is thought that the receptor for AGEs, known as RAGE, may be responsible for inflammation in the retina and, in particular, within cells known as the retinal pigment epithelium (RPE). These interactions could predispose the patient to AMD.

Prof Stitt, who is internationally renowned for his work, said: “We are delighted with these very prestigious awards.

“Queen’s is a centre of excellence for ophthalmic research in the UK, especially in the study of diabetic retinopathy and age-related macular degeneration.

“These grants reflect our international standing and I am convinced that they will make a telling contribution as we seek to understand the underlying causes of major retinal diseases and, importantly, develop new, effective therapeutic interventions”.

More information about the work of the CVS can be found at http://www.qub.ac.uk/research-centres/CentreforVisionSciences

Lisa Mitchell | alfa
Further information:
http://www.qub.ac.uk/
http://www.qub.ac.uk/research-centres/CentreforVisionSciences

More articles from Health and Medicine:

nachricht Penn vet research identifies new target for taming Ebola
12.01.2017 | University of Pennsylvania

nachricht The strange double life of Dab2
10.01.2017 | University of Miami Miller School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

Im Focus: How to inflate a hardened concrete shell with a weight of 80 t

At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).

Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...

Im Focus: Bacterial Pac Man molecule snaps at sugar

Many pathogens use certain sugar compounds from their host to help conceal themselves against the immune system. Scientists at the University of Bonn have now, in cooperation with researchers at the University of York in the United Kingdom, analyzed the dynamics of a bacterial molecule that is involved in this process. They demonstrate that the protein grabs onto the sugar molecule with a Pac Man-like chewing motion and holds it until it can be used. Their results could help design therapeutics that could make the protein poorer at grabbing and holding and hence compromise the pathogen in the host. The study has now been published in “Biophysical Journal”.

The cells of the mouth, nose and intestinal mucosa produce large quantities of a chemical called sialic acid. Many bacteria possess a special transport system...

Im Focus: Newly proposed reference datasets improve weather satellite data quality

UMD, NOAA collaboration demonstrates suitability of in-orbit datasets for weather satellite calibration

"Traffic and weather, together on the hour!" blasts your local radio station, while your smartphone knows the weather halfway across the world. A network of...

Im Focus: Repairing defects in fiber-reinforced plastics more efficiently

Fiber-reinforced plastics (FRP) are frequently used in the aeronautic and automobile industry. However, the repair of workpieces made of these composite materials is often less profitable than exchanging the part. In order to increase the lifetime of FRP parts and to make them more eco-efficient, the Laser Zentrum Hannover e.V. (LZH) and the Apodius GmbH want to combine a new measuring device for fiber layer orientation with an innovative laser-based repair process.

Defects in FRP pieces may be production or operation-related. Whether or not repair is cost-effective depends on the geometry of the defective area, the tools...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

Nothing will happen without batteries making it happen!

05.01.2017 | Event News

 
Latest News

Multiregional brain on a chip

16.01.2017 | Power and Electrical Engineering

New technology enables 5-D imaging in live animals, humans

16.01.2017 | Information Technology

Researchers develop environmentally friendly soy air filter

16.01.2017 | Power and Electrical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>