There are several retinopathies of unknown cause; among them AZOOR, Multifocal choroiditis, Serpiginous choroiditis, Idiopathic Blind Spot Enlargement Syndrome … etc.
The progressive nature of these conditions causes most patients to gradually lose their vision until many of them are left blinded. It must be considered that not only is the diagnosis most patients not easy, especially in the early stages of the disease, but that the identification of faster diagnosis methods would lead to the correct treatment sooner, avoiding in this manner the increasing loss of visual acuity.
Without a doubt, discovering the cause of each of these retinopathies would bring new hope of their treatments. Three years ago, with the help and financial support of ONCE, a research team led by Luis Carrasco professor of microbiology at the Universidad Autónoma de Madrid, noticed that a patient suffering form AZOOR was also infected by a type of yeast called Candida famata. In collaboration with the Clínica Barraquer, these studies have been extended to other patients with AZOOR or with Serpiginous choroiditis.In January this year, information about the fungal infection in these patients was published in the Journal of Clinical Microbiology
(Pisa, D., M. Ramos, P. García, R. Escoto, R. Barraquer, S. Molina y L. Carrasco. Fungal infection in patients with Serpiginous choroiditis or acute zonal occult outer retinopathy. J. Clin. Microbiol. 46, 130-135 (2008)).
To carry out this investigation the researchers analyzed blood samples looking for antibodies against yeasts, as well as different fungal components such as proteins and DNA. These results indicate the existence of a disseminated mycosis in most of the analyzed patients which suggests that retinopathies like AZOOR and Serpiginous choroiditis are caused by fungal infections. Looking for treatments based on current anti fungal drugs could offer great benefits for these patients. The clinical studies about the effects of anti fungal compounds in the evolution of these patients will be crucial to determine whether the presence of mycosis is the cause of the loss of visual acuity.
Future investigations by Dr. Luis Carrasco's research group will lean towards the improvement of diagnosis techniques for fungal infections and the cause of other retinopathies. These techniques will also be useful for the analysis of the evolution and effectiveness of the possible anti fungal treatments that are implemented with these patients.
Hot cars can hit deadly temperatures in as little as one hour
24.05.2018 | Arizona State University
3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg
The more electronics steer, accelerate and brake cars, the more important it is to protect them against cyber-attacks. That is why 15 partners from industry and academia will work together over the next three years on new approaches to IT security in self-driving cars. The joint project goes by the name Security For Connected, Autonomous Cars (SecForCARs) and has funding of €7.2 million from the German Federal Ministry of Education and Research. Infineon is leading the project.
Vehicles already offer diverse communication interfaces and more and more automated functions, such as distance and lane-keeping assist systems. At the same...
A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.
The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...
At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.
At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...
There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?
At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...
So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics
Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...
25.05.2018 | Event News
02.05.2018 | Event News
13.04.2018 | Event News
25.05.2018 | Event News
25.05.2018 | Machine Engineering
25.05.2018 | Life Sciences