A nutritional supplement product, NutraStem also known as NT-020, is a proprietary formulation of blueberry, green tea, vitamin D3 and carnosine extracts- a combination of nutritional ingredients thought to be potent in protecting against brain damage.
“Stroke is the third leading cause of death and the leading cause for disability in the U.S. with two of every 1,000 adults experiencing their firsts stroke in any given year,” said Cesar V. Borlongan, PhD, of the Medical College of Georgia, lead author of a study that tested NT-020 post stroke effects in animal models. “We explored how increasing the nutritive diet through NT-020 supplementation might render a therapeutically potent neurogenesis following stroke.”
NutraStem was developed by Natura Therapeutics, Inc., based in Tampa, Florida and founded by neuroscientists from the University of South Florida.. NutraStem was designed to encourage the proliferation of adult stem cells, which have the potential to develop into most tissues and bone cells in the body and have the capacity to migrate toward problem or damaged areas.
A study, conducted jointly by scientists at the University of South Florida College of Medicine (Tampa) and the Medical College of Georgia (Augusta), examined two groups of laboratory animals in a double-blind procedure. One group received the dietary supplement for two weeks prior to undergoing surgical stroke. The second group did not receive the dietary supplement. Results, published online in the high-impact journal REJUVENATION RESEARCH ), showed that the group receiving NutraStem had greatly reduced neural damage in the brain and demonstrated significantly reduced motor deficits.
”The numbers of new neurons found in the damaged brain of the treated rats was significantly higher,” said co-author Paula Bickford, PhD, of the University of South Florida College of Medicine and co-founder of Natura Therapeutics, Inc. “An important feature of our results is that the combination of agents used was 100 times more potent than previously published study results that examined each of the individual ingredients used by themselves.”
Co-author Cyndy D. Sanberg, PhD, of Natura Therapeutics, Inc., noted that while eliminating detrimental calories has been found to be protective against stroke by reducing oxidative stress, the nutritive diet of NutraStem could enhance and augment that approach.
“Our study found robust neuroprotective effects of the NT-020 formula,” said Borlongan. “Two weeks of NutraStem therapy lessened stroke-induced behavioral deficits, reduced stroke-induced infarcts and promoted the birth of new neurons. Our results provide a critical advance in the scientific and clinical arena by demonstrating the advantage of a multi-agent over a single agent regimen.”
Dr. Cesario V. Borlongan | EurekAlert!
One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center
The gut microbiota plays a key role in treatment with classic diabetes medication
01.06.2017 | University of Gothenburg
An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.
Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...
Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.
Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...
Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.
As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...
Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.
With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...
Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine
Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...
19.06.2017 | Event News
13.06.2017 | Event News
13.06.2017 | Event News
23.06.2017 | Physics and Astronomy
23.06.2017 | Physics and Astronomy
23.06.2017 | Information Technology