Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

GPs' Databases could identify tens of thousands with undiagnosed diabetes

25.02.2008
Researchers, led by the University of Warwick, who examined blood test records in a survey of over 3.6 million patient records held by UK GP surgeries, have found thousands of cases of probable undiagnosed diabetes. This could help identify tens of thousands of people with undiagnosed diabetes in UK.

The research is published in the March issue of the British Journal of General Practice and was led by Dr Tim Holt of the University of Warwick with colleagues from Nottingham University, Egton Medical Information Systems (EMIS) in Leeds, and Imperial College in London. The article is entitled “Identifying undiagnosed diabetes: cross-sectional survey of 3.6 million patients’ electronic records.” The full list of the researchers is detailed below.

The researchers surveyed 3,630,296 electronic patient records in 480 GP surgeries all over the UK which contribute anonymised electronic health record data to the QRESEARCH database in Nottingham for research purposes.

The research team looked for biochemical evidence of undiagnosed diabetes recorded in blood glucose measurements. They first eliminated known patients with diabetes, and cases where raised blood glucose was found but diabetes had already been ruled out as a cause by further tests. They found that this still left 3,758 patients whose last blood glucose level was indicative of undiagnosed diabetes, and 32,785 patients whose last level was at best borderline leaving many of them at significant risk of diabetes and requiring further assessment.

Lead author Dr Tim Holt, from the University of Warwick’s Warwick Medical School, said: “The search was originally piloted in my own practice in Warwickshire, and six individuals were found, most of whom were diagnosed with diabetes on further testing. The majority of practices sampled in the research project included such patients. If the same survey was extended to all UK GP surgeries we estimate that 60,000 people would be identified with evidence of undiagnosed diabetes. In addition, over half a million people nationally would require further tests to rule out diabetes. The study demonstrates the power of information technology to assist practice teams in the early detection of diabetes.”

The researchers were pleased to find how commonly blood glucose test results were recorded- one third of people over 40 years without diabetes have a blood glucose measurement in the past two years in their medical record. Raised or borderline blood glucose levels may not be followed up for a number of reasons that will be the subject of further research. In people without symptoms of diabetes, other more pressing issues may take priority over a borderline test, or the patient may not respond to an invitation for follow up.

It is known that diabetes often goes undiagnosed for years, and there is a large ‘missing population’ of people with diabetes in the UK. Computer searches may be an effective means of identifying some of this population. As a result of this research software has been installed into the majority of UK practices to assist practice staff in identifying possible cases during routine care. This involves screen alert messages and regularly updated lists. The researchers call on all GPs to use the software to improve the early detection of diabetes in the UK.

On searching his own GP practice records Dr Holt found 6 patients who required further follow up. One of those patients, Mr Peter Alexander, a Business Sales Manager from Warwickshire said “I wish that this system had been introduced nationwide much earlier. For everyone it is important to have their health checked regularly, for the good of the country and using this software a lot of people with undiagnosed diabetes may be identified immediately.”

Peter Dunn | alfa
Further information:
http://www.warwick.ac.uk

More articles from Health and Medicine:

nachricht Investigators may unlock mystery of how staph cells dodge the body's immune system
22.09.2017 | Cedars-Sinai Medical Center

nachricht Monitoring the heart's mitochondria to predict cardiac arrest?
21.09.2017 | Boston Children's Hospital

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The pyrenoid is a carbon-fixing liquid droplet

Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.

A warming planet

Im Focus: Highly precise wiring in the Cerebral Cortex

Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.

The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Rainbow colors reveal cell history: Uncovering β-cell heterogeneity

22.09.2017 | Life Sciences

Penn first in world to treat patient with new radiation technology

22.09.2017 | Medical Engineering

Calculating quietness

22.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>