Project Title: Process and Production of Novel “All Natural” Sunscreen Agents
Researchers: O.M. Lai, C. Kong, C.T. Low, S.K. Lo, Rosfarizan Mohd., K. Long and Rosnah Ismail
There has been growing interest in fat and oil modification to form structured lipids, which confers desirable properties for cosmetic, nutritional and pharmaceutical purposes. Structured lipids synthesized can have sun-screening capability and also act as a solvent for dissolving fat-soluble aromatics, steroids or dyes, such as gamma oryzanol, vitamins and phospholipids in respective fields.
The exposure to ultraviolet (UV) radiation originating from sunlight can cause harmful effects on human health, such as erythema (sunburn), melanoma (skin cancer), and premature skin aging. These effects are caused by UVA (320nm to 400nm) and UVB (290nm to 320nm) radiations. Despite the availability of diverse choices of sunscreens, the search for new and improved sunscreens still continues.
This is because limitations of current products such as water solubility of sunscreen, irritation and allergic reaction caused by chemical based sunscreens and oiliness skin feel of the sunscreen itself.
This research provides two alternatives in producing structured lipids that has sun-screening effect. The first method involves the enzymatic esterification reaction between an active compound known as ethyl ferulate with an oil deodorizer distillate to produce a novel sunscreen agent. Ethyl ferulate is a scavenger and is able to neutralize any free radicals generated through long exposure to the UVA and UVB radiations.
The second method requires the production of a carrier phase in sunscreen formulation that contains high purity medium-chain triglycerides (MCT) with gamma-oryzanol as sunscreen agent. This novel method is considerably less expensive than currently known methods as it utilizes relatively inexpensive oil byproducts from the refining process of palm kernel and rice bran oil as starting materials, respectively.
The oil byproducts chosen contain both medium-chain free fatty acids and sunscreen agent. This work involves optimization of parameters for the esterification reaction, formulation of sunscreen and final evaluation of the end product to determine the stability and its effectiveness as a natural sunscreen.
This project has two Malaysian patents pending.
For more information, please contactDr. Nayan KANWAL
Dr Nayan KANWAL, FRSA, ABIM | ResearchSEA
Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University
Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded after a glide flight with an Airbus A320 in ditching on the Hudson River. All 155 people on board were saved.
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded...
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
27.02.2017 | Materials Sciences
27.02.2017 | Interdisciplinary Research
27.02.2017 | Life Sciences