ALA is a fatty acid that cannot be made by the body and must be supplied in the diet. The study will be published in the February 2008 issue of Archives of Ophthalmology.
Dry eye syndrome is a condition in which the eyes do not produce enough tears, causing them to become dry and irritated. Inflammation is frequently associated with the condition. Symptoms of dry eye syndrome include eye discomfort, such as stinging or burning, eye irritation or a feeling of scratchiness. The condition affects well more than 10 million people, primarily women, in the United States alone and can often lead to problems with activities such as reading and driving. Dry eye syndrome is also one of the most common conditions for which patients see eye care. Unfortunately, treatment options are quite limited in terms of both efficacy and undesirable side-effects.
The study tested three formulations of fatty acids: 0.2 percent alpha-linolenic acid (an omega-3 fatty acid) ; 0.2 percent linoleic acid (an omega-6 fatty acid) ; and 0.1 percent alpha-linolenic acid combined with 0.1 percent linoleic acid. An eye drop containing each of the three formulations was applied topically to the eye of a mouse once daily. An untreated group did not receive eye drops. Signs of dry eye were then measured 24 hours after the last dose. Eyes treated with ALA showed a significant reversal in epithelial damage to the cornea, the transparent dome that covers the pupil. Results show a beneficial effect of the topical application of ALA in reversing the signs of dry eye syndrome as well as the inflammatory changes seen in dry eye syndrome.
“The current study for the first time demonstrates the benefit of topical application of a particular fatty acid in treating the signs of dry eye syndrome at both the molecular and cellular levels. Using topical formulations of fatty acids to treat dry eye would allow for more flexibility for treatment, including lessening side effects that patients can experience from oral intake of fatty acids. Clinical studies with topical fatty acids are being planned, which if successful could alter the method by which this common condition is treated,” said Dr. Dana.
Vannessa Carrington | EurekAlert!
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The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
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Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.
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The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.
Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...
Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...
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