Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New principle for developing vaccines

13.12.2007
Infections with a certain type of bacteria (group B streptococcus) can lead to severe, sometimes life-threatening, infections in newborn infants.

In Sweden some 100 children contract these infections each year. Now medical researchers at Lund University are on the track of a possible future vaccine. The method they are using may also be of significance for other new vaccines.

When a new vaccine is developed, it is often done by first selecting a certain protein that characterizes the bacterium or virus the vaccine will be targeting. In the next step a certain part of the protein is singled out that has an especially strong capacity to rouse the body’s immune defense.

The idea of a vaccine is for the immune defense to recognize and react to a future invader. Selected portions of a couple of different proteins are sometimes combined into a so-called fusion protein.

“But we tried another way of thinking. Perhaps the other parts of the protein that don’t provoke the immune defense as much are more important to the protein. They may have been hidden from the immune defense precisely because they are so important,” wonders Gunnar Lindahl, professor of medical microbiology.

A new fusion protein based on this idea turned out to have the very best effect on group B streptococci­just the opposite of the conventional principles.

“This discovery is significant not only for battling streptococci but also for developing new vaccines in general. The conventional way of going about it might not be the most effective,” maintains Gunnar Lindahl.

A vaccine against group B streptococci would probably be given to young women ahead of their first pregnancy. One possibility would be to do this in combination with the vaccine against cervical cancer that was launched earlier this year and targets teenage girls prior to their sexual debut.

The findings are published in Cell Host & Microbe, a new sister journal of the prestigious Cell­.

Ingela Björck | alfa
Further information:
http://www.cellhostandmicrobe.com/

More articles from Health and Medicine:

nachricht Hot cars can hit deadly temperatures in as little as one hour
24.05.2018 | Arizona State University

nachricht 3D images of cancer cells in the body: Medical physicists from Halle present new method
16.05.2018 | Martin-Luther-Universität Halle-Wittenberg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

When corals eat plastics

24.05.2018 | Ecology, The Environment and Conservation

Surgery involving ultrasound energy found to treat high blood pressure

24.05.2018 | Medical Engineering

First chip-scale broadband optical system that can sense molecules in the mid-IR

24.05.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>