The novel approach that will be tested in the routine diagnosis of lymphoma in the Department of Pathology is based on a new biomarker, i.e., a factor that is specific for a certain disease. The discovery is a result of research within CREATE Health, a Center for Translational Cancer Research supported by the Foundation for Strategic Research and the Wallenberg Foundation.
CREATE Health has integrated investigators from the faculties of medicine, engineering, and natural sciences together with clinical oncologists from the university hospital. The overall aim is to identify proteins and genes that can be used as biomarkers for cancer, using emerging advanced technologies. Several very promising projects are under development, but the novel diagnostic approach for MCL has advanced the furthest. Scientist Sara Ek and colleagues have by studying more than 50,000 gene fragments found those that are specifically overexpressed in this disease. She has also identified the corresponding proteins and it is one of these proteins that serves as a specific biomarker.
- In a collaboration with pathologists, we are now studying the biomarker to see if it can be used as a novel routine test for this aggressive blood cancer. In a longer perspective, knowledge about the function of these disease-specific proteins can also lead to novel therapeutic modalities for blood cancer, explains professor Carl Borrebaeck, program director for CREATE Health.Dr. Michael Dictor, pathologist at Lund University Hospital agrees.
Ingela Bjoerck | alfa
Observing the cell's protein factories during self-assembly
15.06.2018 | Charité - Universitätsmedizin Berlin
Scientists unravel molecular mechanisms of Parkinson's disease
13.06.2018 | The Francis Crick Institute
Moving into its fourth decade, AchemAsia is setting out for new horizons: The International Expo and Innovation Forum for Sustainable Chemical Production will take place from 21-23 May 2019 in Shanghai, China. With an updated event profile, the eleventh edition focusses on topics that are especially relevant for the Chinese process industry, putting a strong emphasis on sustainability and innovation.
Founded in 1989 as a spin-off of ACHEMA to cater to the needs of China’s then developing industry, AchemAsia has since grown into a platform where the latest...
The BMBF-funded OWICELLS project was successfully completed with a final presentation at the BMW plant in Munich. The presentation demonstrated a Li-Fi communication with a mobile robot, while the robot carried out usual production processes (welding, moving and testing parts) in a 5x5m² production cell. The robust, optical wireless transmission is based on spatial diversity; in other words, data is sent and received simultaneously by several LEDs and several photodiodes. The system can transmit data at more than 100 Mbit/s and five milliseconds latency.
Modern production technologies in the automobile industry must become more flexible in order to fulfil individual customer requirements.
An international team of scientists has discovered a new way to transfer image information through multimodal fibers with almost no distortion - even if the fiber is bent. The results of the study, to which scientist from the Leibniz-Institute of Photonic Technology Jena (Leibniz IPHT) contributed, were published on 6thJune in the highly-cited journal Physical Review Letters.
Endoscopes allow doctors to see into a patient’s body like through a keyhole. Typically, the images are transmitted via a bundle of several hundreds of optical...
Light detection and control lies at the heart of many modern device applications, such as smartphone cameras. Using graphene as a light-sensitive material for...
Water molecules exist in two different forms with almost identical physical properties. For the first time, researchers have succeeded in separating the two forms to show that they can exhibit different chemical reactivities. These results were reported by researchers from the University of Basel and their colleagues in Hamburg in the scientific journal Nature Communications.
From a chemical perspective, water is a molecule in which a single oxygen atom is linked to two hydrogen atoms. It is less well known that water exists in two...
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