Researchers from the University of Strathclyde and Stanford University in California are creating a prosthetic retina for patients of age related macular degeneration (AMD), which affects one in 500 patients aged between 55 and 64 and one in eight aged over 85.
The device would be simpler in design and operation than existing models. It acts by electrically stimulating neurons in the retina, which are left relatively unscathed by the effects of AMD while other ‘image capturing’ cells, known as photoreceptors, are lost.
It would use video goggles to deliver energy and images directly to the eye and be operated remotely via pulsed near infra-red light- unlike most prosthetic retinas, which are powered through coils that require complex surgery to be implanted.
The prosthetic retina is a thin silicon device that converts pulsed near infra-red light to electrical current that stimulates the retina and elicits visual perception. It requires no wires and would make surgical implantation simpler.
The device has been shown to produce encouraging responses in initial lab tests and is reported in an article published in Nature Photonics. The technology is now being developed further.
Dr Keith Mathieson, now a Reader in the Institute of Photonics at the University of Strathclyde in Glasgow, was one of the lead researchers and first author of the paper. He said: “AMD is a huge medical challenge and, with an aging population, is continuing to grow. This means that innovative, practical solutions are essential if sight is to be restored to people around the world with the condition.
“The prosthetic retina we are developing has been partly inspired by cochlear implants for the ear but with a camera instead of a microphone and, where many cochlear implants have a few channels, we are designing the retina to deal with millions of light sensitive nerve cells and sensory outputs.
“The implant is thin and wireless and so is easier to implant. Since it receives information on the visual scene through an infra-red beam projected through the eye, the device can take advantage of natural eye movements that play a crucial role in visual processing.”
The research was co-authored by Dr. Jim Loudin of Stanford and led by Professor Daniel Palanker, also of Stanford, and Professor Alexander Sher, of the University of California, Santa Cruz.
Professor Palanker said: "The current implants are very bulky, and the surgery to place the intraocular wiring for receiving, processing and power is difficult. With our device, the surgeon needs only to create a small pocket beneath the retina and then slip the photovoltaic cells inside it."
Dr Mathieson was supported through a fellowship from SU2P, a venture between academic institutions in Scotland and California aimed at extracting economic impact from their joint research portfolio in photonics and related technologies.
Strathclyde leads the collaboration, which also includes Stanford, the Universities of St Andrews, Heriot-Watt and Glasgow and the California Institute of Technology. SU2P was established through funding from Research Councils UK- as part of its Science Bridges awards- the Scottish Funding Council and Scottish Enterprise.
The research links to Photonics and Health Technologies at Strathclyde- two of the principal themes of the University’s Technology and Innovation Centre (TIC), a world-leading research and technology centre transforming the way universities, business, and industry collaborate.
Through Health Technologies at Strathclyde, academics work with industry and the health sector to find technologies for earlier, more accurate disease detection and better treatments, as well as life-long disease prevention.The article in Nature Photonics can be seen at
Paul Gallagher | EurekAlert!
Millions through license revenues
27.04.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
New High-Performance Center Translational Medical Engineering
26.04.2017 | Fraunhofer ITEM
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
28.04.2017 | Event News
20.04.2017 | Event News
18.04.2017 | Event News
28.04.2017 | Medical Engineering
28.04.2017 | Earth Sciences
28.04.2017 | Life Sciences