Research shows probiotic strain prevents uptake of mercury and arsenic in children and pregnant women in Tanzania
New research shows probiotic yogurt can reduce the uptake of certain heavy metals and environmental toxins by up to 78% in pregnant women. Led by Scientists at Lawson Health Research Institute's Canadian Centre for Human Microbiome and Probiotic Research, this study provides the first clinical evidence that a probiotic yogurt can be used to reduce the deadly health risks associated with mercury and arsenic.
Environmental toxins like mercury and arsenic are commonly found in drinking water and food products, especially fish. These contaminants are particularly high in areas where mining and agriculture are prevalent, and in the developing world where regulations for industrial activities are limited or poorly enforced.
Even at low levels, chronic exposure to heavy metals has been linked to certain cancers and delayed neurological and cognitive development in children. Yet in Canada, 15% of reproductive-aged women possess mercury levels that pose a high risk for neurodevelopmental abnormalities in their children.
Research suggests some naturally occurring bacteria in the body can influence toxic metal levels. Lactobacillus rhamnosus GR-1 is a probiotic strain that has already been used safely and effectively in yogurt in Canada with positive immune benefits. Previous lab research at Lawson showed it can also bind to heavy metals, but clinical research was needed to confirm whether this mechanism would prevent the body from absorbing them.
In the study, Dr. Gregor Reid, a Scientist at Lawson and Western University, and Jordan Bisanz and Megan Enos, trainees at Lawson and graduate students at Western, assessed 44 school-aged children and 60 pregnant women living in Mwanza, Tanzania near Lake Victoria. This area is known for having particularly high environmental pollution.
Tanzania is also home to a network of community yogurt kitchens previously set up with the scientists to provide a locally-sourced, low-cost source of nutrition. The goal of the study was to assess existing metal levels in the environment and participants' bodies, map their natural bacteria to identify any potential links to metal absorption, and determine whether the probiotic-supplemented yogurt could influence metal absorption.
The scientists found mercury and lead levels were up to seven times higher than what is typically found in Canadian children. Silver cyprinids, small fish consumed widely in the region, were found to contain especially high levels of mercury and arsenic. DNA sequencing identified two bacteria present in children with the highest concentrations of heavy metals, suggesting the presence of these bacteria may be linked to metal absorption.
After consuming the probiotic-supplemented yogurt, the children showed positive, but not statistically effective, results. The pregnant women showed more dramatic outcomes. The probiotic yogurt protected them from further uptake of mercury by up to 36% and arsenic by up to 78%.
"The findings are exciting for many reasons," says Dr. Reid, senior author on the publication. "First, they show a simple fermented food, easily made by resource disadvantaged communities, can provide benefits in addition to nutrition and immunity. Second, the results are relevant for many parts of the world, including Canada, where exposure to these toxins occurs daily. Finally, it confirms more attention needs to be paid to these toxins, especially in children and pregnant women."
"Seeing the children, you would never think they were walking around with such high levels of toxins," says Bisanz, the first author on the paper. "I hate to think of the consequences for them as they age. The children and pregnant women all loved the yogurt. If we could only scale up these yogurt kitchen concepts, the impact on quality of life could be massive."
This study was funded in part by the Bill and Melinda Gates Foundation. The study is published today in mBio, the journal of the American Society for Microbiology, available here: http://mbio.asm.org/content/5/5/e01580-14
Lawson Health Research Institute. As the research institute of London Health Sciences Centre and St. Joseph's Health Care London, and working in partnership with Western University, Lawson Health Research Institute is committed to furthering scientific knowledge to advance health care around the world. http://www.lawsonresearch.com
For more information, please contact:
Sonya Gilpin | Eurek Alert!
Millions through license revenues
27.04.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
New High-Performance Center Translational Medical Engineering
26.04.2017 | Fraunhofer ITEM
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
28.04.2017 | Event News
20.04.2017 | Event News
18.04.2017 | Event News
28.04.2017 | Medical Engineering
28.04.2017 | Earth Sciences
28.04.2017 | Life Sciences