The probability of blindness due to the serious eye disease glaucoma has decreased by nearly half since 1980, according to a study published this month in Ophthalmology, the journal of the American Academy of Ophthalmology.
The researchers speculate that advances in diagnosis and therapy are likely causes for the decrease, but caution that a significant proportion of patients still progress to blindness.
A leading cause of irreversible blindness worldwide, glaucoma affects more than 2.7 million individuals aged 40 and older in the United States and 60.5 million people globally. Significant changes in diagnostic criteria, new therapies and tools as well as improvements in glaucoma management techniques have benefited individual patients; however their effect on the rates of visual impairment on a population level has remained unclear. This study, conducted by a team based at the Mayo Clinic, was the first to assess long-term changes in the risk of progression to blindness and the population incidence of glaucoma-related blindness. By identifying epidemiologic trends in glaucoma, the researchers hope to gain insight into best practices for the distribution of health and medical resources, as well as management approaches for entire populations.
The researchers reviewed every incident case (857 cases total) of open-angle glaucoma (OAG)--the most common form of glaucoma--diagnosed from 1965 to 2009 in Olmsted County, Minn., one of the few places in the world where long-term population-based studies are conducted. They found that the 20-year probability and the population incidence of blindness due to OAG in at least one eye had decreased from 25.8 percent for subjects diagnosed between 1965 and 1980 to 13.5 percent for those diagnosed between 1981 and 2000. The population incidence of blindness within 10 years of diagnosis also decreased from 8.7 per 100,000 to 5.5 per 100,000 for those groups, respectively. Yet, 15 percent of the patients diagnosed in the more recent timeframe still progressed to blindness.
"These results are extremely encouraging for both those suffering from glaucoma and the doctors who care for them, and suggest that the improvements in the diagnosis and treatment have played a key role in improving outcomes," said Arthur J. Sit, M.D., associate professor of ophthalmology at the Mayo Clinic College of Medicine and lead researcher for the study. "Despite this good news, the rate at which people continue to go blind due to OAG is still unacceptably high. This is likely due to late diagnosis and our incomplete understanding of glaucoma, so it is critical that research into this devastating disease continues, and all eye care providers be vigilant in looking for early signs of glaucoma during routine exams."
The American Academy of Ophthalmology recommends that all adults receive a baseline eye exam by age 40, and for seniors age 65 and older to have an eye exam every one to two years or as directed by an ophthalmologist. For more information about glaucoma and other eye conditions, visit http://www.geteyesmart.org.
About the American Academy of Ophthalmology
The American Academy of Ophthalmology, headquartered in San Francisco, is the world's largest association of eye physicians and surgeons--Eye M.D.s--with more than 32,000 members worldwide. Eye health care is provided by the three "O's" – ophthalmologists, optometrists, and opticians. It is the ophthalmologist, or Eye M.D., who has the education and training to treat it all: eye diseases, infections and injuries, and perform eye surgery. For more information, visit http://www.aao.org. The Academy's EyeSmart® program educates the public about the importance of eye health and empowers them to preserve healthy vision. EyeSmart provides the most trusted and medically accurate information about eye diseases, conditions and injuries. OjosSanos™ is the Spanish-language version of the program. Visit http://www.geteyesmart.org or http://www.ojossanos.org to learn more.
Ophthalmology, the official journal of the American Academy of Ophthalmology, publishes original, peer-reviewed, clinically applicable research. Topics include the results of clinical trials, new diagnostic and surgical techniques, treatment methods technology assessments, translational science reviews and editorials.
Media Relations | EurekAlert!
It don't mean a thing if the brain ain't got that swing
28.07.2015 | University of California - Berkeley
MSU scientists set sights on glaucoma medication to treat TB
24.07.2015 | Michigan State University
Researchers have developed an ultrafast light-emitting device that can flip on and off 90 billion times a second and could form the basis of optical computing.
Joint BioEnergy Institute study identifies bacterial protein that is key to protecting rice against bacterial blight
A bacterial signal that when recognized by rice plants enables the plants to resist a devastating blight disease has been identified by a multi-national team...
Researchers in the Cockrell School of Engineering at The University of Texas at Austin are one step closer to delivering smart windows with a new level of energy efficiency, engineering materials that allow windows to reveal light without transferring heat and, conversely, to block light while allowing heat transmission, as described in two new research papers.
By allowing indoor occupants to more precisely control the energy and sunlight passing through a window, the new materials could significantly reduce costs for...
Argonne scientists used Mira to identify and improve a new mechanism for eliminating friction, which fed into the development of a hybrid material that exhibited superlubricity at the macroscale for the first time. Argonne Leadership Computing Facility (ALCF) researchers helped enable the groundbreaking simulations by overcoming a performance bottleneck that doubled the speed of the team's code.
While reviewing the simulation results of a promising new lubricant material, Argonne researcher Sanket Deshmukh stumbled upon a phenomenon that had never been...
A NASA camera on the Deep Space Climate Observatory (DSCOVR) satellite has returned its first view of the entire sunlit side of Earth from one million miles away.
The color images of Earth from NASA's Earth Polychromatic Imaging Camera (EPIC) are generated by combining three separate images to create a...
23.07.2015 | Event News
10.07.2015 | Event News
25.06.2015 | Event News
28.07.2015 | Life Sciences
28.07.2015 | Materials Sciences
28.07.2015 | Ecology, The Environment and Conservation