Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Predicting post-traumatic stress disorder before it happens

14.06.2012
Tel Aviv University researchers use brain imaging to uncover susceptibility to psychological stress and trauma

Most people have intense emotional reactions to traumatizing events like road accidents or combat. But some suffer far longer, caught in the grip of long-term debilitating disorders such as Post-Traumatic Stress Disorder (PTSD).

Because doctors cannot predict who will develop these disorders, however, early or preventive intervention is not available. Now, a new project led by researchers at Tel Aviv University seeks to identify pre-traumatic subjects — those who are more susceptible to long-standing disorders if exposed to a traumatic incident.

The project, a joint work between Prof. Talma Hendler of TAU's School of Psychological Sciences, the Sackler Faculty of Medicine and the new Sagol School of Neuroscience, and Prof. Nathan Intrator of TAU's Blavatnik School of Computer Science and the Sagol School of Neuroscience, uses electroencephalography (EEG) and functional magnetic resonance imaging (fMRI) to investigate the areas of the brain that regulate the emotional response to traumatic stress, then decode the brain functionality which indicates pre- or post trauma psychopathology.It's a powerful and novel approach to probing the susceptible brain and providing ongoing monitoring tailored to each individual.

This ongoing interdisciplinary research was done at the Functional Brain Center in collaboration with the Wohl Institute for Advanced Imaging at the Tel Aviv Sourasky Medical Center.

Taking PTSD personally

The earlier and more accurately PTSD is diagnosed, the more likely a healthcare provider can treat it. And beyond their diagnostic capabilities, the research findings could be used to monitor people who will be at high risk for developing these disorders, such as soldiers in combat units.

Diagnosis and treatment of mental disorders depends on understanding how the brain encodes and regulates emotions. For example, certain combinations of activities in emotional and cognitive brain areas may better indicate an individual's susceptibility to traumatic disorders than studying each area by itself, believes Prof. Hendler. In the last few years, the researchers have published on these issues in leading scientific journals including PNAS and Cerebral Cortex.

To look at the interactions between areas of the brain, study participants were monitored using EEG (which records electrical activity along the scalp) and fMRI (which measures changes in blood oxygenation in the brain) concurrently. Connections between the emotional and cognitive areas of the brain were recorded as subjects were exposed to continuous stimulations designed to cause stress and other emotional effects such as horror and sadness. Using advanced computational algroithms, the researchers identified the brain activity that was connected to the reported emotional experience. This brain marking will provide targets for therapeutic procedures based on a person's individual brain activity.

With these experiments, the researchers hope to improve their ability to read emotional states in the depths of the human brain. While they are currently working with EEG and fMRI, Prof. Intrator hopes that in the later stages of development they will be able to read results collected by EEG alone. Initial findings were recently presented at the prestigious Neural Information Processing Systems Conference and published in the journals Brain Connectivity and Neuroimage.

Diagnostics on the go

Ultimately, the researchers hope to develop a portable brain monitoring machine that will "enable the detection or quantification of the emotional state of people suffering from trauma," allowing for minimally invasive monitoring or diagnosis, says Prof. Intrator. He is working on applying this technology to the diagnosis of additional psychological disorders, including schizophrenia, depression, and attention deficit disorder (ADD) for the better management of these diseases. In the case of ADD, for example, this method could be used to monitor the level of concentration in a patient, and provide feedback that could help to regulate the patient's medicinal needs, such as the dosage of Ritalin.

Some of these projects are part of the newly-formed Israel Brain Technology (IBT) initiative, launched by Israeli President Shimon Peres and run by entrepreneur Rafi Gidron. IBT leverages technology and knowledge from Israeli universities to help Israel become a power player in neurotechnology.

American Friends of Tel Aviv University (www.aftau.org) supports Israel's leading, most comprehensive and most sought-after center of higher learning. Independently ranked 94th among the world's top universities for the impact of its research, TAU's innovations and discoveries are cited more often by the global scientific community than all but 10 other universities.

Internationally recognized for the scope and groundbreaking nature of its research and scholarship, Tel Aviv University consistently produces work with profound implications for the future.

George Hunka | EurekAlert!
Further information:
http://www.aftau.org

Further reports about: Aviv Brain IBT Israeli Neuroscience PTSD Predicting Psychological Science brain area mental disorder

More articles from Health and Medicine:

nachricht Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine

nachricht Flexible sensors can detect movement in GI tract
11.10.2017 | Massachusetts Institute of Technology

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

Im Focus: New nanomaterial can extract hydrogen fuel from seawater

Hybrid material converts more sunlight and can weather seawater's harsh conditions

It's possible to produce hydrogen to power fuel cells by extracting the gas from seawater, but the electricity required to do it makes the process costly. UCF...

Im Focus: Small collisions make big impact on Mercury's thin atmosphere

Mercury, our smallest planetary neighbor, has very little to call an atmosphere, but it does have a strange weather pattern: morning micro-meteor showers.

Recent modeling along with previously published results from NASA's MESSENGER spacecraft -- short for Mercury Surface, Space Environment, Geochemistry and...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

Conference Week RRR2017 on Renewable Resources from Wet and Rewetted Peatlands

28.09.2017 | Event News

 
Latest News

A single photon reveals quantum entanglement of 16 million atoms

16.10.2017 | Physics and Astronomy

The melting ice makes the sea around Greenland less saline

16.10.2017 | Earth Sciences

On the generation of solar spicules and Alfvenic waves

16.10.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>