The next big thing in cancer treatment may be hotter, covered in more gold, and even be a better swimmer than recent Olympic champion Michael Phelps.
Scientists at the University of Idaho are engineering multifunctional and dynamic nanowires coated in gold that swim through the bloodstream and attach to specific cancerous cells. Once there, an electromagnetic field heats the nanowires, which destroys the targeted cells. The research is supported by a new $425,000 grant, part of a multimillion dollar project funded by the Korean government as part of the International Global Collaboration Pioneer Program.
“Cancer is a dangerous enemy because radiation and chemical treatments cause a lot of side effects,” said Daniel Choi, associate professor of materials science and engineering at the University of Idaho and leader of the project. “We can’t avoid side effects 100 percent, but these nanowires will minimize the damage to healthy cells.”
The technology involves many steps requiring lots of continuing research, but each of the basic concepts already have been proven in laboratory tests.
Choi and his team have already created nanowires that can “swim” to their targets and heat up when exposed to low frequency electromagnetic fields, which are not harmful to human body. The next step is to make them biocompatible, meaning safe to introduce to the human body, and able to seek out specific cancer cells.
Choi believes the gold plating will take care of the biocompatibility. If not, he has several polymers in mind that he also believes would work.
As for seeking out specific cancer cells, Choi also is a member of and working with a University of Idaho group called BANTech – an interdisciplinary group that integrates nanomaterials research with cell biology and bioscience research. The group has identified several promising candidates for antibodies with which to coat the nanowires that would seek out and attach to specific cancer cells.
Once the technology has proven itself in the laboratory, it will be tested in live animals, and eventually human beings. Several Korean institutions, which are helping in every phase of research, will take the lead in that project. The institutions are Seoul National University, Korea University and the Korea Institute of Science and Technology.
“Collaborating with Korean institutions has been a wonderful experience full of mutual benefits and great achievements,” said Choi. “Multi-institutional, multi-national projects can provide students and researchers with opportunities to engage in cutting-edge investigations within an international research environment, which is very important to advancing science.”
Nanoparticles as a Solution against Antibiotic Resistance?
15.12.2017 | Friedrich-Schiller-Universität Jena
Plasmonic biosensors enable development of new easy-to-use health tests
14.12.2017 | Aalto University
DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
15.12.2017 | Power and Electrical Engineering
15.12.2017 | Materials Sciences
15.12.2017 | Life Sciences