Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

People with peanut allergy can react to lupin

08.12.2008
During her doctoral work, Lise Holden developed a method of identifying lupin protein in food products. She also investigated the incidence of lupin allergy among children with food allergy and studied the proteins in lupin responsible for allergy production.

Several hundred species of lupin exist. Lupin seed, rich in protein and fibre, has formed part of the diet of some southern European and south American countries for centuries. Many are cultivated as house plants, but these are inedible. Selective breeding has given us the sweet lupin, which tastes good and has a lower content of alkaloids than previous variants.

During recent years, the use of sweet lupin has become more widespread throughout Europe. Lupin-based ingredients improve both the nutritional value and baking qualities of food, and they are commonly added to wheaten flour. Another use is as a replacement for soya, since many consumers associate soya with gene manipulation. In addition, lupin seed is gluten-free and can therefore be safely eaten by people afflicted with coeliac disease. New studies indicate that lupin protein can have cholesterol-reducing properties.

The increased use of lupin in food has led to several reported cases of allergic reactions against lupin, including in Norway. Lupin may produce allergy either by primary sensitisation or through cross-reaction with other legumes, especially peanut. People with peanut allergy should therefore be aware that they can react to food labelled as containing lupin.

Authorities, producers and sufferers all need a reliable way of identifying even small amounts of allergens in food. For her doctorate, Lise Holden developed a quantitative and sensitive immunological method for demonstrating lupin protein. The method, the first of its kind, now forms the basis of a commercial kit developed in co-operation with an English firm, HAVen. This method was utilised in a comprehensive investigation of lupin in food for the Norwegian market in 2006 - 2007, which showed that lupin is used in many different types of food such as bread, biscuits, cakes, pasta and chocolate spreads. Even though consumers are exposed to lupin in their food, lupin allergy remains a relatively rare form of allergy in Norway today.

Holden and her colleagues have in clinical studies of children conducted provocation testing with lupin. Many of the children had lupin-specific antibody in their blood without showing clinical allergy, demonstrating just how important provocation testing is for accurate diagnosis of lupin allergy.

In addition, Lise Holden worked with the identification of specific proteins in lupin that may produce allergy. Mapping such proteins may lead to a better understanding of allergy in its entirety.

Cand. scient. Lise Holden defended her thesis for Ph. D. degree, entitled "Lupin - a new food allergen: studies on the detection, antigenicity and allergenicity of lupin proteins", on October 17, 2008.

Magnhild Jenssen | alfa
Further information:
http://www.veths.no
http://www.veths.no/105/English/Kima/People-with-peanut-allergy-can-react-to-lupin/

More articles from Health and Medicine:

nachricht Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine

nachricht Flexible sensors can detect movement in GI tract
11.10.2017 | Massachusetts Institute of Technology

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Ocean atmosphere rife with microbes

17.10.2017 | Life Sciences

Neutrons observe vitamin B6-dependent enzyme activity useful for drug development

17.10.2017 | Life Sciences

NASA finds newly formed tropical storm lan over open waters

17.10.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>