Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Pacemaker in stomach helps against vomiting

29.03.2010
People with severe stomach disorders can sometimes suffer from chronic vomiting. This symptom can be treated with electrical impulses from a pacemaker in the stomach.

A new method enables patients who could benefit from this treatment to be identified, and electrical stimulation leads to reduced nausea and fewer days in hospital, shows a study from the Sahlgrenska Academy at the University of Gothenburg, Sweden.

Gastric electrical stimulation has previously been shown to be effective in most diabetics who suffer from severe vomiting due to the disease. New research shows that people with other severe stomach disorders could also benefit from this treatment.

27 patients were included in a study testing electrical stimulation of the stomach. 22 had fewer symptoms as a result of initial temporary stimulation, and 20 of these then had a permanent pacemaker surgically inserted into the stomach. Of the patients who responded well to temporary stimulation, 90% also had good results in a long-term follow-up of the surgically inserted pacemaker. The treatment led to reduced nausea and vomiting. In another study of 16 patients, electrical stimulation led to fewer days in hospital in the year following treatment.

Simple temporary stimulation through the skin can be used to identify the patients who could benefit from the treatment.

"We insert gastric electrodes into the patient under local anaesthesia through a small incision in the skin, and these are then connected to an external pacemaker," explains junior doctor Stina Andersson, a doctoral student at the Department of Internal Medicine. "If the results are positive, we can be relatively certain that treatment with a surgically inserted pacemaker will work for that patient. The next step is to insert a pacemaker using keyhole surgery."

Based on these studies and previous research, gastric electrical stimulation does not seem to affect the stomach locally.

"We believe instead that the stimulation somehow acts on the brain's centre for nausea and vomiting by activating the neural pathways running from the stomach to the brain," says Andersson.

Some diabetics with severe symptoms are already being treated clinically with a gastric pacemaker. Other patients with hard-to-treat gastrointestinal disorders could also now receive the treatment following careful examination and successful temporary stimulation of the stomach.

"The treatment could, for example, work on intractable nausea following chemotherapy or extreme nausea during pregnancy," says Andersson. "No studies have yet been performed in these areas, however."

Stomach disorders
Severe vomiting and nausea may be caused by a condition known as gastroparesis, where the stomach empties very slowly without there being any blockage. The causes of gastroparesis can include diabetes and gastric surgery. In addition, around 20% of the Swedish population is believed to have functional dyspepsia, or gastric catarrh. Here, the stomach empties normally but symptoms such as chronic nausea and vomiting can occur in more severe cases.
For more information, please contact:
Stina Andersson, junior doctor, tel. +46(0)703 083070, e-mail mailto:stina.anna.andersson@vgregion.se
Thesis for the degree of Doctor of Philosophy (Medicine) at the Department of Internal Medicine, Institute of Medicine, Sahlgrenska Academy
Title of thesis: Gastric electrical stimulation. Studies in patients with intractable nausea and vomiting.

The thesis has been defended.

Helena Aaberg | idw
Further information:
http://hdl.handle.net/2077/21862
http://www.gu.se/

More articles from Health and Medicine:

nachricht Cholesterol-lowering drugs may fight infectious disease
22.08.2017 | Duke University

nachricht Once invincible superbug squashed by 'superteam' of antibiotics
22.08.2017 | University at Buffalo

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

What the world's tiniest 'monster truck' reveals

23.08.2017 | Life Sciences

Treating arthritis with algae

23.08.2017 | Life Sciences

Witnessing turbulent motion in the atmosphere of a distant star

23.08.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>