This approach guarantees that the ionizing radiation only destroys tumorous cells and does not affect other organs in the vicinity of the prostate. In a cooperative study with Innsbruck Medical University and the East-Vienna Center of Social Medicine, two physicists of Vienna University of Technology (TU), evaluated the mean deviation of radiation parameters for prostate cancers and compared various sources of radiation.
Movement inaccuracies of up to two centimeters may occur in prostate radiation. “During the radiation treatment, patients have to lie on a table for some 20 minutes without moving. Over time, the muscles relax and the pelvis drops. As a consequence, the radiation may focus on the bladder or other organs. In our calculations, we concentrated on the precision of localizing the prostate and on improvement potentials in treatment,” explained Karin Poljanc, Assistant Professor at the Atomic Institute of Austrian Universities.
In a study conducted in cooperation with SMZ Ost (East-Vienna Center of Social Medicine, Danube Hospital), Poljanc and her research associates, Tanja Futschek and Leila Teymournia, used a number of ultrasound examinations that allowed for a precise localization of the patients’ organs from the outside. In a next step, the scientists analyzed the positioning of 60 patients, and evaluated the deviation of radiation in various spatial directions, such as to the right or left, and upward or downward (using 420 radiation plans for thirty patients). While it takes more time, an ultrasound system makes the shifts in position visible and traceable. If the deviation exceeds 0.8 cm, the radiology technicians are responsible for returning the patient to the correct position to ensure that the radiation only targets the specified area. In the subsequent study phase, Poljanc and her group calculated normal tissue compensation rates and the probability of tumor control. “This provides us with an overview of the probability that the tumor is targeted directly and the probability of side effects for individual patients,” notes Poljanc. These approaches serve as forecasts and provide clues for the likelihood of healing.
After a study period of some 2.5 years, with generous sponsorship of the Anniversary Fund of the Austrian National Bank, the scientists were able to implement the calculated average positioning inaccuracies in a radiation planning system. Sums up Leila Teymournia: “Depending on the calculation model used, the normal tissue compensation rate can vary widely in the results. While the use of Model A may yield a negligible complication rate, the same process calculated with Model B shows a deviation of up to 40 percent.” Due to the absence of biological parameters, major discrepancies may result with different models. Nevertheless, the results of calculations can provide physicians with data for improving patient positioning accuracy and therefore, and improvement of treatment success.
As part of their study of different radiation sources, Karin Poljanc, Tanja Futschek, and Leila Teymournia found that localization aids, such as ultrasound systems, are indispensable for accurate proton therapy of prostate carcinomas. In most cases, this combination leads to therapy results with a high level of tissue preservation.
The future establishment of the cancer research and therapy center “Med-AUSTRON” in Wiener Neustadt will implement such a treatment method in Austria.
Daniela Hallegger | alfa
Resolving the mystery of preeclampsia
21.10.2016 | Universitätsklinikum Magdeburg
New potential cancer treatment using microwaves to target deep tumors
12.10.2016 | University of Texas at Arlington
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences