Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Obesity hormone adiponectin increases the risk of osteoporosis in the elderly

02.11.2011
While obesity is a well-known cause of cardiovascular disease, research from the Sahlgrenska Academy at the University of Gothenburg, Sweden, has now revealed that the body’s obesity hormones – adiponectin - are also linked to osteoporosis and an increased risk of fractures.

Our skeleton is more than just bones, vertebrae and joints. In fact, it is an active organ that is constantly linked to our brain, our muscles and our fatty tissue. Stem cells – the body’s most important cells – are formed in the skeleton, which is also home to hormones that control the body’s blood sugar and obesity by sending signals to other organs.

New research has now revealed that raised levels of obesity hormone in the blood could be connected to osteoporosis.

Dan Mellström, a researcher at the Sahlgrenska Academy and consultant at Sahlgrenska University Hospital, is a leading expert in osteoporosis. As part of an international research project studying the risk factors associated with osteoporosis in elderly men, he and his colleagues have been looking into the obesity hormone adiponectin. This research has now shown that people with raised levels of this hormone also have more fragile skeletons and more fractures, as well as reduced muscle strength and lower muscle mass, increasing the risk of fractures. High adiponectin also seems to be related to increased functional ageing.

“High levels of adiponectin in the elderly seem to be associated with both reduced functioning of the musculature and a more fragile skeleton,” says Mellström. “This means a higher risk of fractures and falls, and also increased mortality.”

The results are based on the Mr OS study, led from the Sahlgrenska Academy, which is looking into the risk factors for osteoporosis in elderly men. The study includes around 11,000 men in Sweden, the USA and Hong Kong.

OSTEOPOROSIS
Osteoporosis, or brittle bone disease, involves a reduction in the strength of the skeleton as a result of illness or ageing. The disorder causes much suffering for those affected it and also considerable costs to society. It is estimated that one third of all care places in Swedish orthopaedic clinics go to patients with hip fractures or complications from hip fractures.
For more information, please contact: Professor Dan Mellström
Telephone: +46 (0)31 343 9035
Mobile: +46 (0)703 247 510
E-mail: dan.mellstrom@vgregion.se

Helena Aaberg | idw
Further information:
http://www.gu.se

More articles from Health and Medicine:

nachricht Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign

nachricht Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>