Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Nano-capsules show potential for more potent chemoprevention

08.01.2014
Researchers at the Winship Cancer Institute of Emory University have discovered a more effective drug delivery system using nanotechnology that could one day significantly affect cancer prevention.

The study, published today in Cancer Prevention Research, a journal of the American Association for Cancer Research, involved the use of microscopic amounts of the naturally occurring antioxidant, luteolin, that were encapsulated in a water-soluble polymer. When injected into mice the nano-luteolin inhibited growth of lung cancer and head and neck cancer cells.

"Our results suggest that nanoparticle delivery of naturally occurring dietary agents like luteolin has many advantages," says senior study author Dong Moon Shin, MD, professor of hematology and medical oncology at Emory University School of Medicine and associate director of academic development at Winship Cancer Institute. "By using a high concentration of luteolin in the blood, we were better able to inhibit the growth of cancer cells."

Luteolin is known for its anti-inflammatory and anti-cancer effects. It is naturally found in green vegetables such as broccoli, celery and artichokes, however, Shin says large quantities would need to be consumed to be effective. By concentrating the compound into a nanoparticle and making it easy to dissolve in water, researchers conclude nano-luteolin has immense potential for future human studies of chemoprevention

Chemoprevention is currently used to help stop the recurrence of cancer in patients and reduce the risk of cancer in others.

Winship Cancer Institute of Emory University is Georgia's only National Cancer Institute-Designated Cancer Center and serves as the coordinating center for cancer research and care throughout Emory University. For over 75 years, Winship has served the citizens of Georgia and the Southeast by working tirelessly to prevent, treat and cure cancer.

To learn more about the Winship Cancer Institute of Emory University, its research, outreach, clinical trials and faculty and staff, visit http://winshipcancer.emory.edu.

Judy Fortin | EurekAlert!
Further information:
http://www.emory.edu

More articles from Health and Medicine:

nachricht UT Southwestern scientists discover new clues to how weight loss is regulated
24.10.2014 | UT Southwestern Medical Center

nachricht Bipolar Disorder Discovery at the Nano Level
23.10.2014 | Northwestern University

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Anzeige

Anzeige

Event News

Comparing Apples and Oranges? A Colloquium on International Comparative Urban Research

22.10.2014 | Event News

Battery Conference April 2015 in Aachen

16.10.2014 | Event News

Experts discuss new developments in the field of stem cell research and cell therapy

10.10.2014 | Event News

 
Latest News

Precise and programmable biological circuits

24.10.2014 | Life Sciences

Desert Streams: Deceptively Simple

24.10.2014 | Earth Sciences

Modernized stainless steel continuous caster from Siemens goes on stream at Posco

24.10.2014 | Press release

VideoLinks
B2B-VideoLinks
More VideoLinks >>>