Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Monitoring can be the right choice for local prostate cancer

22.06.2010
Monitoring can be the best treatment for men with prostate cancer of the low-risk type, according to a study now being published in the Journal of the National Cancer Institute. The lead author is Pär Stattin, a urologist at Umeå University.

How local prostate cancer, that is, cancer that has not spread outside the prostate gland, should be treated is a controversial issue. In many cases such tumors grow only very slowly, and one treatment strategy is to monitor them rather than to actively intervene directly.

Pär Stattin and his associates evaluated the outcomes for 6,849 men aged up to 70 years in the Swedish National Prostate Cancer Registry (NPCR) who had a local tumor with low or moderately high risk of spreading. During the years 1997-2002 monitoring of 2,021 of these men commenced, while 3,399 had their prostate gland surgically removed and 1,429 received radiation treatment.

With a median follow-up time of over 8 years, the researchers find that the risk of dying of prostate cancer within ten years was a total of 3.6 % in the group that was monitored (2.4 % with low-risk tumors and 5.2 % with tumors of moderately high risk) and somewhat lower among men who underwent active treatment: 2.5 % among those who were operated on and 3.3 % among those receiving radiation. The risk of dying from causes other than cancer was nearly twice as high among men who were monitored, which indicates that men with other conditions and shorter estimated remaining lifetimes were monitored more often than more healthy men.

The authors of the study conclude that monitoring of tumor development is the best alternative for many men with local prostate cancer of the low-risk type. Besides Pär Stattin, co-authors are Erik Holmberg and Jonas Hugosson, both with the Sahlgrenska Academy, Gothenburg University; Jan-Erik Johansson, University Hospital in Örebro; Lars Holmberg, King's College, London, UK; and Jan Adolfsson, Karolinska Institute.

For more information, please contact Professor Pär Stattin, Department of Surgical and Perioperative Science, Division of Urology and Andrology, Umeå University,
phone: +46 (0)90-785 2291
mobile: +46 (0)73-620 52 51
e-mail par.stattin@urologi.umu.se
Reference
P Stattin, E Holmberg, JE Johansson, L Holmberg, J Adolfsson, J Hugosson Outcomes in Localized Prostate Cancer: National Prostate Cancer Register of Sweden Follow-up Study

JNCI Journal of the National Cancer Institute 2010; doi: 10.1093/jnci/djq154

Hans Fällman | idw
Further information:
http://www.umu.se
http://www.umu.se/digitalAssets/19/19714_stattin_par__mg_3409_090907_mpn.jpg

More articles from Health and Medicine:

nachricht Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan

nachricht Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Start codons in DNA may be more numerous than previously thought

21.02.2017 | Life Sciences

An alternative to opioids? Compound from marine snail is potent pain reliever

21.02.2017 | Life Sciences

Warming ponds could accelerate climate change

21.02.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>