How local prostate cancer, that is, cancer that has not spread outside the prostate gland, should be treated is a controversial issue. In many cases such tumors grow only very slowly, and one treatment strategy is to monitor them rather than to actively intervene directly.
Pär Stattin and his associates evaluated the outcomes for 6,849 men aged up to 70 years in the Swedish National Prostate Cancer Registry (NPCR) who had a local tumor with low or moderately high risk of spreading. During the years 1997-2002 monitoring of 2,021 of these men commenced, while 3,399 had their prostate gland surgically removed and 1,429 received radiation treatment.
With a median follow-up time of over 8 years, the researchers find that the risk of dying of prostate cancer within ten years was a total of 3.6 % in the group that was monitored (2.4 % with low-risk tumors and 5.2 % with tumors of moderately high risk) and somewhat lower among men who underwent active treatment: 2.5 % among those who were operated on and 3.3 % among those receiving radiation. The risk of dying from causes other than cancer was nearly twice as high among men who were monitored, which indicates that men with other conditions and shorter estimated remaining lifetimes were monitored more often than more healthy men.
The authors of the study conclude that monitoring of tumor development is the best alternative for many men with local prostate cancer of the low-risk type. Besides Pär Stattin, co-authors are Erik Holmberg and Jonas Hugosson, both with the Sahlgrenska Academy, Gothenburg University; Jan-Erik Johansson, University Hospital in Örebro; Lars Holmberg, King's College, London, UK; and Jan Adolfsson, Karolinska Institute.For more information, please contact Professor Pär Stattin, Department of Surgical and Perioperative Science, Division of Urology and Andrology, Umeå University,
JNCI Journal of the National Cancer Institute 2010; doi: 10.1093/jnci/djq154
Hans Fällman | idw
Speed data for the brain’s navigation system
06.12.2016 | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)
Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
06.12.2016 | Materials Sciences
06.12.2016 | Medical Engineering
06.12.2016 | Power and Electrical Engineering