Painkilling drugs that make many therapies possible are a blessing for patients. Thanks to modern anesthetics, not only can surgical operations be conducted without causing pain, they are also used for various diagnostic procedures.
In the ‘Constraint-Induced Movement Therapy’ (CIMT) the healthy arm is being restrained in a cuff, while the stroke-affected arm and hand are intensely training fine motor skills.
Photo: Jan-Peter Kasper/FSU
Anesthetics can be very useful in therapies for stroke patients, as psychologists and physicians of the Friedrich Schiller University Jena (Germany) and the University Hospital Jena are now able to prove.
In the ‘Journal of Neuroscience’ (DOI:10.1523/JNEUROSCI.5912-11.2012) the researchers present the results of their study, showing how a local anesthetic can distinctly improve the motor skills of patients after a stroke.
“Many stroke patients suffer from chronic impairment of the hand or of the complete arm,” Professor Dr. Thomas Weiss explains. Together with expert colleagues the psychologist of the department of Biological and Clinical Psychology at Jena University has been working for a number of years on a specialized medical training therapy which clearly enhances the mobility of stroke patients. In the ‘Constraint-Induced Movement Therapy’ (CIMT) the healthy arm is being restrained in a cuff, while the stroke-affected arm and hand are intensely training fine motor skills. Patients are asked to carry out tasks such as stacking small toy blocks or putting tiny pins into a perforated board. Daily activities like washing one’s hand are part of the training.“Nearly every affected person benefits from this training,” Weiss‘s colleague Prof. Dr. Wolfgang Miltner says. The chair of Biological and Clinical Psychology developed the therapy together with American colleagues and refers to the comprehensive study results about the efficiency of the program. “We are happy to carry out this therapy on many patients - together with our colleagues from the psychology department in the neurological day hospital,” the director of the clinic for Neurology, Prof. Dr. Otto Witte, stresses.
“Unsurprisingly, the motor performance of all patients was strongly enhanced,” Prof. Weiss commented on the result. “Beyond that, it became obvious that the patients who received the anesthetic benefited even more than the placebo group,“ Weiss says. The researchers could show the reason for this effect using magnetoencephalographic imaging (MEG) of the patients. The temporary interruption of nerve impulses from the forearm leads to a decreasing activity in the brain areas processing these impulses. “At the same time neighboring brain cells are activated more strongly,” the Jena Psychologist explains. Thus the brain reacts to the missing impulses from the forearm with an increased sensitivity in the hand as the MEG images showed. Consequently the motor performance improves as well. “This process starts within minutes,” Thomas Weiss says.
A subsequent study is going to show whether the combination of local anesthetics and therapeutic exercise will improve the mobility of stroke patients in the long term.Original Publication:
Dr. Ute Schönfelder | idw
Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan
Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
20.02.2017 | Materials Sciences
20.02.2017 | Health and Medicine
20.02.2017 | Health and Medicine