Painkilling drugs that make many therapies possible are a blessing for patients. Thanks to modern anesthetics, not only can surgical operations be conducted without causing pain, they are also used for various diagnostic procedures.
In the ‘Constraint-Induced Movement Therapy’ (CIMT) the healthy arm is being restrained in a cuff, while the stroke-affected arm and hand are intensely training fine motor skills.
Photo: Jan-Peter Kasper/FSU
Anesthetics can be very useful in therapies for stroke patients, as psychologists and physicians of the Friedrich Schiller University Jena (Germany) and the University Hospital Jena are now able to prove.
In the ‘Journal of Neuroscience’ (DOI:10.1523/JNEUROSCI.5912-11.2012) the researchers present the results of their study, showing how a local anesthetic can distinctly improve the motor skills of patients after a stroke.
“Many stroke patients suffer from chronic impairment of the hand or of the complete arm,” Professor Dr. Thomas Weiss explains. Together with expert colleagues the psychologist of the department of Biological and Clinical Psychology at Jena University has been working for a number of years on a specialized medical training therapy which clearly enhances the mobility of stroke patients. In the ‘Constraint-Induced Movement Therapy’ (CIMT) the healthy arm is being restrained in a cuff, while the stroke-affected arm and hand are intensely training fine motor skills. Patients are asked to carry out tasks such as stacking small toy blocks or putting tiny pins into a perforated board. Daily activities like washing one’s hand are part of the training.“Nearly every affected person benefits from this training,” Weiss‘s colleague Prof. Dr. Wolfgang Miltner says. The chair of Biological and Clinical Psychology developed the therapy together with American colleagues and refers to the comprehensive study results about the efficiency of the program. “We are happy to carry out this therapy on many patients - together with our colleagues from the psychology department in the neurological day hospital,” the director of the clinic for Neurology, Prof. Dr. Otto Witte, stresses.
“Unsurprisingly, the motor performance of all patients was strongly enhanced,” Prof. Weiss commented on the result. “Beyond that, it became obvious that the patients who received the anesthetic benefited even more than the placebo group,“ Weiss says. The researchers could show the reason for this effect using magnetoencephalographic imaging (MEG) of the patients. The temporary interruption of nerve impulses from the forearm leads to a decreasing activity in the brain areas processing these impulses. “At the same time neighboring brain cells are activated more strongly,” the Jena Psychologist explains. Thus the brain reacts to the missing impulses from the forearm with an increased sensitivity in the hand as the MEG images showed. Consequently the motor performance improves as well. “This process starts within minutes,” Thomas Weiss says.
A subsequent study is going to show whether the combination of local anesthetics and therapeutic exercise will improve the mobility of stroke patients in the long term.Original Publication:
Dr. Ute Schönfelder | idw
One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center
The gut microbiota plays a key role in treatment with classic diabetes medication
01.06.2017 | University of Gothenburg
An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.
Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...
Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.
Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...
Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.
As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...
Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.
With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...
Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine
Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...
19.06.2017 | Event News
13.06.2017 | Event News
13.06.2017 | Event News
23.06.2017 | Physics and Astronomy
23.06.2017 | Physics and Astronomy
23.06.2017 | Information Technology