A new study led by researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) compares traditional "open" surgery to remove the stomach with laparoscopic gastrectomy – a minimally invasive procedure in which the surgeon removes the stomach while guided by a magnified image projected by a thin, lighted tube with a video camera at its tip, called a laparoscope.
The findings demonstrate that while laparoscopic surgeries generally took longer to perform than open procedures, the minimally invasive approach yielded shorter hospital stays, decreased need for postoperative pain relief, fewer complications after surgery, and similar rates of recurrence-free survival after 36 months of follow-up.
"Our number one goal in treating patients with stomach cancer is to remove the cancer completely and safely, while preserving his or her quality of life," says the study's lead author Vivian E. Strong, MD, a surgeon at MSKCC who specializes in laparoscopic surgery for the treatment of stomach cancer, also known as gastric cancer. "Laparoscopic gastrectomy is an excellent option for certain patients with the disease, and for those patients, this approach has the same success rate as standard open surgery, with significantly fewer complications."
Published online in the Annals of Surgical Oncology, the paper describes the largest US study of laparoscopic gastrectomy to date and demonstrates both the safety and efficacy of the procedure. The study examined the surgical characteristics and oncologic outcomes of 30 patients who underwent laparoscopic gastrectomy and compared them to 30 patients who had open gastrectomies. The patients in each group were matched for cancer stage, age, and gender, and had their surgeries during the same time period.
In addition to the benefits seen among the patients who underwent laparoscopic gastrectomy, researchers also observed that this approach enabled adequate lymph node retrieval, an important part of a complete cancer surgery in which nearby nodes are removed and then carefully examined for the presence of cancer cells to determine whether the cancer has spread. According to the authors, this finding addresses an ongoing controversy that questions whether removal of the lymph nodes and other oncologic features of the resection during laparoscopic gastrectomy are equivalent to open surgery, particularly given the technical demands of the minimally invasive approach and the learning curve required to perform an adequate resection.
"Laparoscopic gastrectomy is a technically advanced surgical procedure," Dr. Strong notes. "Patients considering it should go to hospitals with a high volume of gastric cancer cases, and choose a surgeon who has extensive experience performing the laparoscopic procedure."
MSKCC is one of the few National Cancer Institute–designated cancer centers with a specific program in treating cancers of the upper gastrointestinal tract, which includes the stomach. About 100 gastrectomies, both open and laparoscopic, are performed each year at MSKCC – one of the highest volumes of surgery for this relatively rare cancer of any center in the country. The first laparoscopic gastrectomy performed at MSKCC was in 2001, and since 2005 more than 75 patients have had their stomach cancers treated laparoscopically.
Despite the fact that each year approximately 22,000 Americans are diagnosed with stomach cancer, surgeons in the US have much less experience with laparoscopic gastrectomy than those in Korea and Japan, where many more cases of gastric cancer are treated and larger studies have been published demonstrating it to be a safe, effective, and well-accepted technique.
The study's authors include Daniel Coit, MD, Murray F. Brennan, FACS, Peter J. Allen, MD, and Nicolas Devaud, MD, of the Department of Surgery, and Mithat Gonen, PhD of the Department of Epidemiology and Biostatistics. The research was funded by the Department of Surgery at MSKCC.
Memorial Sloan-Kettering Cancer Center is the world's oldest and largest private institution devoted to prevention, patient care, research, and education in cancer. Our scientists and clinicians generate innovative approaches to better understand, diagnose, and treat cancer. Our specialists are leaders in biomedical research and in translating the latest research to advance the standard of cancer care worldwide.
Esther Napolitano | EurekAlert!
New High-Performance Center Translational Medical Engineering
26.04.2017 | Fraunhofer ITEM
A promising target for kidney fibrosis
21.04.2017 | Brigham and Women's Hospital
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
20.04.2017 | Event News
18.04.2017 | Event News
03.04.2017 | Event News
26.04.2017 | Materials Sciences
26.04.2017 | Agricultural and Forestry Science
26.04.2017 | Physics and Astronomy