Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New method to diagnose sinusitis could reduce use of antibiotics

07.10.2011
A new method of diagnosing sinusitis is presented in a new thesis from Lund University. The results offer the potential to reduce the use of antibiotics and the costs of the disease to society.

Sinusitis is a very common disease and exists in both an acute and a chronic form. In Europe, over nine per cent of the population suffers from chronic sinusitis.

The author of the thesis is Pernilla Sahlstrand Johnson, a PhD student and ear, nose and throat doctor at Lund University and Skåne University Hospital. In the work on the thesis, she and her colleagues at the Faculty of Engineering at Lund University tested and evaluated a new method to better diagnose sinusitis.

The method employs a Doppler ultrasound sensor, which, unlike a normal ultrasound or CT scan, can determine the viscosity of the sinus fluid. Until now, the only way to find this out for certain has been by flushing out the maxillary sinuses, which is an unpleasant procedure for the patient.

Only patients with thick sinus fluid are considered to need antibiotics, while for those with thin fluid there are other effective treatment options.

“Antibiotic resistance is seen as a growing problem. One in four people in Sweden takes antibiotics at least once a year, and many of these have been diagnosed with sinusitis. A more accurate diagnosis could reduce the amount of antibiotics prescribed and the right treatment could also reduce costs”, says Pernilla Sahlstrand Johnson. “We have used the new method in the laboratory with good results. We are planning to trial the Doppler ultrasound sensor in a clinical environment soon, on a number of patients at the Ear, Nose and Throat Clinic at Skåne University Hospital in Malmö and Lund.”

Pernilla Sahlstrand Johnson has also studied the self-perceived quality of life of a group of just over 200 patients awaiting sinus surgery. As well as the Ear, Nose and Throat Clinics in Skåne, patients at Karolinska and Sahlgrenska University Hospitals have also completed questionnaires for the study, which is one of the largest of its kind.

Both general questionnaires and questionnaires specific to sinusitis have been used, and the answers shed light on the patients’ perceived quality of life and mental health and their absence from work. The responses indicate high levels of absence – patients reported 8–14 days of sick leave in the course of a year resulting from their sinus problems.

“The participants in our study experienced a significant fall in quality of life as a result of their sinusitis – greater than in other large patient groups with diseases such as angina or cancer. Sinusitis probably also has a major financial impact on society, as it is a common disease and leads to relatively high levels of sick leave”, says Pernilla Sahlstrand Johnson.

Pernilla Sahlstrand Johnson defended her thesis on 30 September 2011. The title of the thesis is "On health-related quality of life and diagnostic improvement in rhinosinusitis"

Pernilla Sahlstrand Johnson: +46 40 33 23 34, +46 733 36 95 54, pernilla.sahltrand_johnson@med.lu.se.

For a downloadable photograph of Pernilla Sahlstrand Johnson, search for Pernilla Sahlstrand in the Lund University image bank: http://bildweb.srv.lu.se/.

Referenslänk: thesis is "On health-related quality of life and diagnostic improvement in rhinosinusitis"

Megan Grindlay | idw
Further information:
http://www.lu.se/o.o.i.s?id=12588&postid=2117512

More articles from Health and Medicine:

nachricht Biofilm discovery suggests new way to prevent dangerous infections
23.05.2017 | University of Texas at Austin

nachricht Another reason to exercise: Burning bone fat -- a key to better bone health
19.05.2017 | University of North Carolina Health Care

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>