Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New method to diagnose sinusitis could reduce use of antibiotics

07.10.2011
A new method of diagnosing sinusitis is presented in a new thesis from Lund University. The results offer the potential to reduce the use of antibiotics and the costs of the disease to society.

Sinusitis is a very common disease and exists in both an acute and a chronic form. In Europe, over nine per cent of the population suffers from chronic sinusitis.

The author of the thesis is Pernilla Sahlstrand Johnson, a PhD student and ear, nose and throat doctor at Lund University and Skåne University Hospital. In the work on the thesis, she and her colleagues at the Faculty of Engineering at Lund University tested and evaluated a new method to better diagnose sinusitis.

The method employs a Doppler ultrasound sensor, which, unlike a normal ultrasound or CT scan, can determine the viscosity of the sinus fluid. Until now, the only way to find this out for certain has been by flushing out the maxillary sinuses, which is an unpleasant procedure for the patient.

Only patients with thick sinus fluid are considered to need antibiotics, while for those with thin fluid there are other effective treatment options.

“Antibiotic resistance is seen as a growing problem. One in four people in Sweden takes antibiotics at least once a year, and many of these have been diagnosed with sinusitis. A more accurate diagnosis could reduce the amount of antibiotics prescribed and the right treatment could also reduce costs”, says Pernilla Sahlstrand Johnson. “We have used the new method in the laboratory with good results. We are planning to trial the Doppler ultrasound sensor in a clinical environment soon, on a number of patients at the Ear, Nose and Throat Clinic at Skåne University Hospital in Malmö and Lund.”

Pernilla Sahlstrand Johnson has also studied the self-perceived quality of life of a group of just over 200 patients awaiting sinus surgery. As well as the Ear, Nose and Throat Clinics in Skåne, patients at Karolinska and Sahlgrenska University Hospitals have also completed questionnaires for the study, which is one of the largest of its kind.

Both general questionnaires and questionnaires specific to sinusitis have been used, and the answers shed light on the patients’ perceived quality of life and mental health and their absence from work. The responses indicate high levels of absence – patients reported 8–14 days of sick leave in the course of a year resulting from their sinus problems.

“The participants in our study experienced a significant fall in quality of life as a result of their sinusitis – greater than in other large patient groups with diseases such as angina or cancer. Sinusitis probably also has a major financial impact on society, as it is a common disease and leads to relatively high levels of sick leave”, says Pernilla Sahlstrand Johnson.

Pernilla Sahlstrand Johnson defended her thesis on 30 September 2011. The title of the thesis is "On health-related quality of life and diagnostic improvement in rhinosinusitis"

Pernilla Sahlstrand Johnson: +46 40 33 23 34, +46 733 36 95 54, pernilla.sahltrand_johnson@med.lu.se.

For a downloadable photograph of Pernilla Sahlstrand Johnson, search for Pernilla Sahlstrand in the Lund University image bank: http://bildweb.srv.lu.se/.

Referenslänk: thesis is "On health-related quality of life and diagnostic improvement in rhinosinusitis"

Megan Grindlay | idw
Further information:
http://www.lu.se/o.o.i.s?id=12588&postid=2117512

More articles from Health and Medicine:

nachricht Investigators may unlock mystery of how staph cells dodge the body's immune system
22.09.2017 | Cedars-Sinai Medical Center

nachricht Monitoring the heart's mitochondria to predict cardiac arrest?
21.09.2017 | Boston Children's Hospital

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: The pyrenoid is a carbon-fixing liquid droplet

Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.

A warming planet

Im Focus: Highly precise wiring in the Cerebral Cortex

Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.

The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...

Im Focus: Tiny lasers from a gallery of whispers

New technique promises tunable laser devices

Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...

Im Focus: Ultrafast snapshots of relaxing electrons in solids

Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!

When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...

Im Focus: Quantum Sensors Decipher Magnetic Ordering in a New Semiconducting Material

For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.

Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

“Lasers in Composites Symposium” in Aachen – from Science to Application

19.09.2017 | Event News

I-ESA 2018 – Call for Papers

12.09.2017 | Event News

EMBO at Basel Life, a new conference on current and emerging life science research

06.09.2017 | Event News

 
Latest News

Rainbow colors reveal cell history: Uncovering β-cell heterogeneity

22.09.2017 | Life Sciences

Penn first in world to treat patient with new radiation technology

22.09.2017 | Medical Engineering

Calculating quietness

22.09.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>