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Mediterranean diet may lower risk of brain damage that causes thinking problems

A Mediterranean diet may help people avoid the small areas of brain damage that can lead to problems with thinking and memory, according to a study released today that will be presented at the American Academy of Neurology's 62nd Annual Meeting in Toronto April 10 to April 17, 2010.

The study found that people who ate a Mediterranean-like diet were less likely to have brain infarcts, or small areas of dead tissue linked to thinking problems.

The Mediterranean diet includes high intake of vegetables, legumes, fruits, cereals, fish and monounsaturated fatty acids such as olive oil; low intake of saturated fatty acids, dairy products, meat and poultry; and mild to moderate amounts of alcohol.

For the study, researchers assessed the diets of 712 people in New York and divided them into three groups based on how closely they were following the Mediterranean diet. Then they conducted MRI brain scans of the people an average of six years later. A total of 238 people had at least one area of brain damage.

Those who were most closely following a Mediterranean-like diet were 36 percent less likely to have areas of brain damage than those who were least following the diet. Those moderately following the diet were 21 percent less likely to have brain damage than the lowest group.

"The relationship between this type of brain damage and the Mediterranean diet was comparable with that of high blood pressure," said study author Nikolaos Scarmeas, MD, MSc, of Columbia University Medical Center in New York and a member of the American Academy of Neurology. "In this study, not eating a Mediterranean-like diet had about the same effect on the brain as having high blood pressure."

Previous research by Scarmeas and his colleagues showed that a Mediterranean-like diet may be associated with a lower risk of Alzheimer's disease and may lengthen survival in people with Alzheimer's disease. According to the present study, these associations may be partially explained by fewer brain infarcts.

The study was supported by the National Institutes of Health.

The American Academy of Neurology, an association of more than 22,000 neurologists and neuroscience professionals, is dedicated to promoting the highest quality patient-centered neurologic care. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Parkinson's disease, ALS (Lou Gehrig's disease), dementia, West Nile virus, and ataxia. For more information about the American Academy of Neurology and the AAN Annual Meeting, visit

Editor's Notes: Study authors are available for advance interviews. Please contact Rachel Seroka, Non-late-breaking abstracts to be presented at the AAN Annual Meeting will be posted online in advance of the AAN Annual Meeting at 4 pm, ET, Wednesday, February 17, 2010, at

Late-breaking abstracts will not be posted online in advance of the Annual Meeting and will remain embargoed until the date and time of presentation of the late-breaking abstract at the AAN Annual Meeting in Toronto, April 10-17, 2010. Late-breaking abstracts will be featured in press release and in press conference at the 2010 AAN Annual Meeting in Toronto. To register to attend the AAN Annual Meeting Press Room in Toronto, visit

Rachel Seroka | EurekAlert!
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