Endemic in South America, the American trypanosomiasis, or Chagas disease, is transmitted to humans via the parasite Trypanosoma cruzi. The disease is usually transmitted through the bite of an infected insect or ‘kissing bug’. The symptoms are variable, but as the disease progresses serious chronic symptoms can appear, such as heart disease and malformation of the intestines. Most people affected may remain without symptoms for years, making diagnosis difficult.
About the Study
The article “Identification of Novel Diagnostic Serum Biomarkers for Chagas’ Disease in Asymptomatic Subjects by Mass Spectrometric Profiling,” published in The Journal of Clinical Microbiology, was co-authored by Momar Ndao and Brian J. Ward from the RI of the MUHC and McGill University; Terry W. Spithill from McGill University and Charles Stuart University and Cynthia Santamaria from McGill University; Rebecca Caffrey from University of California, Berkeley; Hongshan Li from High School of Business, California; Vladimir N. Podust from Vermillion Inc., California, Regis Perichon from Diagnostic Biomarker Evaluation Group Ortho-Clinical Diagnostics, New Jersey; Alberto Ache from Ministerio de Salud y Desarrollo Social, Caracas, Venezuela; Mark Duncan, University of Colorado and Malcolm R. Powell from Western Carolina University and Universidad del Valle Guatemala.
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