Lung function declines as chest deformity deepens

“These results confirm what we have observed anecdotally, that children with more severe pectus excavatum report more incidents of shortness of breath and a higher degree of exercise intolerance,” said one of the study's lead authors, Dr. Robert Kelly, a pediatric surgeon at Children's Hospital of The King's Daughters in Norfolk, Virginia.

Pectus excavatum, a condition sometimes known as sunken chest, occurs when the chest cartilage grows abnormally and the chest wall progressively collapses. A CHKD surgeon, Dr. Donald Nuss, developed a minimally invasive surgery to correct the condition 25 years ago, and the hospital has remained at the forefront of treatment and research on chest wall deformities ever since.

The study on lung function included 327 pre-correction pectus excavatum patients ages 6 to 21 from hospitals around the nation, including CHKD. The study used standardized medical measurements to determine the severity of the pectus excavatum and a spirometer, a device that measures the volume of air expelled from the lungs, to assess lung function.

“The results suggest a correlation between the severity of pectus excavatum and lung function,” said Dr. Kelly. “The more severe the deformity, the more lung function was compromised.” He noted that the effect was primarily from lung restriction, not airway obstruction.

While the decline is relatively modest, Dr. Kelly believes researchers next need to study lung function in pectus excavatum patients at the larger tidal volumes required during exercise.

The study included collaborators from more than 10 hospitals including Cincinnati Children's Hospital, Children's Hospital Boston, Children's Mercy Hospital in Kansas City and the Hospital for Sick Children at the University of Toronto.

Children's Hospital of The King's Daughters is the only freestanding children's hospital in Virginia and serves the medical and surgical needs of children throughout Eastern Virginia and Northeastern North Carolina.

Media Contact

Greg Raver-Lampman EurekAlert!

More Information:

http://www.chkd.org

All latest news from the category: Health and Medicine

This subject area encompasses research and studies in the field of human medicine.

Among the wide-ranging list of topics covered here are anesthesiology, anatomy, surgery, human genetics, hygiene and environmental medicine, internal medicine, neurology, pharmacology, physiology, urology and dental medicine.

Back to home

Comments (0)

Write a comment

Newest articles

Silicon Carbide Innovation Alliance to drive industrial-scale semiconductor work

Known for its ability to withstand extreme environments and high voltages, silicon carbide (SiC) is a semiconducting material made up of silicon and carbon atoms arranged into crystals that is…

New SPECT/CT technique shows impressive biomarker identification

…offers increased access for prostate cancer patients. A novel SPECT/CT acquisition method can accurately detect radiopharmaceutical biodistribution in a convenient manner for prostate cancer patients, opening the door for more…

How 3D printers can give robots a soft touch

Soft skin coverings and touch sensors have emerged as a promising feature for robots that are both safer and more intuitive for human interaction, but they are expensive and difficult…

Partners & Sponsors