"These results confirm what we have observed anecdotally, that children with more severe pectus excavatum report more incidents of shortness of breath and a higher degree of exercise intolerance," said one of the study's lead authors, Dr. Robert Kelly, a pediatric surgeon at Children's Hospital of The King's Daughters in Norfolk, Virginia.
Pectus excavatum, a condition sometimes known as sunken chest, occurs when the chest cartilage grows abnormally and the chest wall progressively collapses. A CHKD surgeon, Dr. Donald Nuss, developed a minimally invasive surgery to correct the condition 25 years ago, and the hospital has remained at the forefront of treatment and research on chest wall deformities ever since.
The study on lung function included 327 pre-correction pectus excavatum patients ages 6 to 21 from hospitals around the nation, including CHKD. The study used standardized medical measurements to determine the severity of the pectus excavatum and a spirometer, a device that measures the volume of air expelled from the lungs, to assess lung function.
"The results suggest a correlation between the severity of pectus excavatum and lung function," said Dr. Kelly. "The more severe the deformity, the more lung function was compromised." He noted that the effect was primarily from lung restriction, not airway obstruction.
While the decline is relatively modest, Dr. Kelly believes researchers next need to study lung function in pectus excavatum patients at the larger tidal volumes required during exercise.
The study included collaborators from more than 10 hospitals including Cincinnati Children's Hospital, Children's Hospital Boston, Children's Mercy Hospital in Kansas City and the Hospital for Sick Children at the University of Toronto.
Children's Hospital of The King's Daughters is the only freestanding children's hospital in Virginia and serves the medical and surgical needs of children throughout Eastern Virginia and Northeastern North Carolina.
Greg Raver-Lampman | EurekAlert!
Speed data for the brain’s navigation system
06.12.2016 | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)
Study suggests possible new target for treating and preventing Alzheimer's
02.12.2016 | Oregon Health & Science University
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
07.12.2016 | Earth Sciences
07.12.2016 | Earth Sciences
07.12.2016 | Materials Sciences