Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Lifestyles of the old and healthy defy expectations

03.08.2011
People who live to 95 or older are no more virtuous than the rest of us in terms of their diet, exercise routine or smoking and drinking habits, according to researchers at Albert Einstein College of Medicine of Yeshiva University.

Their findings, published today in the online edition of Journal of the American Geriatrics Society, suggests that "nature" (in the form of protective longevity genes) may be more important than "nurture" (lifestyle behaviors) when it comes to living an exceptionally long life. Nir Barzilai, M.D., the Ingeborg and Ira Leon Rennert Chair of Aging Research and director of the Institute for Aging Research at Einstein, was the senior author of the study.

Dr. Barzilai and his Einstein colleagues interviewed 477 Ashkenazi Jews who were living independently and were 95 and older (95-112, 75 percent of them women). They were enrolled in Einstein's Longevity Genes Project, an ongoing study that seeks to understand why centenarians live as long as they do. (Descended from a small founder group, Ashkenazi Jews are more genetically uniform than other populations, making it easier to spot gene differences that are present.)

The elderly participants were asked about their lifestyles at age 70, considered representative of the lifestyle they'd followed for most of their adult lives. They answered questions about their weight and height so that their body mass index (BMI) could be calculated. They also provided information about their alcohol consumption, smoking habits, physical activity, and whether they ate a low-calorie, low-fat or low-salt diet.

To compare these long-lived individuals with the general population, the researchers used data from 3,164 people who had been born around the same time as the centenarians and were examined between 1971 and 1975 while participating in the National Health and Nutrition Examination Survey (NHANES I).

Overall, people with exceptional longevity did not have healthier habits than the comparison group in terms of BMI, smoking, physical activity, or diet. For example, 27 percent of the elderly women and an equal percentage of women in the general population attempted to eat a low-calorie diet. Among long-living men, 24 percent consumed alcohol daily, compared with 22 percent of the general population. And only 43 percent of male centenarians reported engaging in regular exercise of moderate intensity, compared with 57 percent of men in the comparison group.

"In previous studies of our centenarians, we've identified gene variants that exert particular physiology effects, such as causing significantly elevated levels of HDL or 'good' cholesterol," said Dr. Barzilai, who is also professor of medicine and of genetics at Einstein. "This study suggests that centenarians may possess additional longevity genes that help to buffer them against the harmful effects of an unhealthy lifestyle."

The research did find, however, that overweight centenarians tended to have lower rates of obesity than the control group. Although male and female centenarians were just as likely to be overweight as their counterparts in the general population, the centenarians were significantly less likely to become obese: only 4.5 percent of male centenarians were obese vs. 12.1 percent of controls; and for women, 9.6 percent of centenarians were obese versus 16.2 percent of controls. Both of these differences are statistically significant.

While longevity genes may protect centenarians from bad habits, healthy lifestyle choices remain critical for the vast majority of the population. The U.S. Census Bureau estimates there were nearly 425,000 people aged 95 and older living in the U.S. in 2010 − a fraction (.01) of the 40 million U.S. adults 65 and over.

"Although this study demonstrates that centenarians can be obese, smoke and avoid exercise, those lifestyle habits are not good choices for most of us who do not have a family history of longevity," said Dr. Barzilai. "We should watch our weight, avoid smoking and be sure to exercise, since these activities have been shown to have great health benefits for the general population, including a longer lifespan."

Researchers also asked study participants why they believed they had lived so long. Most did not attribute their advanced age to lifestyle factors. One-third reported a history of family longevity, while 20 percent believed that physical activity also played a role in their lifespan. Other factors included positive attitude (19 percent), busy or active life (12 percent), less smoking and drinking (15 percent), good luck (8 percent), and religion or spirituality (6 percent).

The paper is titled "Lifestyle Factors of People with Exceptional Longevity." Other Einstein authors were Yingheng Liu, Ph.D., Orit Ben-David, Saritha Reddy, M.B.B.S., Gil Atzmon, Ph.D., and Jill Crandall, M.D., Swapnil N. Rajpathak, M.B.B.S., Dr.PH., now at Merck Pharmaceuticals, was the study's lead author. The research was supported by grants from the National Institute on Aging of the National Institutes of Health.

About Albert Einstein College of Medicine of Yeshiva University

Albert Einstein College of Medicine of Yeshiva University is one of the nation's premier centers for research, medical education and clinical investigation. During the 2009-2010 academic year, Einstein is home to 722 M.D. students, 243 Ph.D. students, 128 students in the combined M.D./Ph.D. program, and approximately 350 postdoctoral research fellows. The College of Medicine has 2,775 fulltime faculty members located on the main campus and at its clinical affiliates. In 2009, Einstein received more than $155 million in support from the NIH. This includes the funding of major research centers at Einstein in diabetes, cancer, liver disease, and AIDS. Other areas where the College of Medicine is concentrating its efforts include developmental brain research, neuroscience, cardiac disease, and initiatives to reduce and eliminate ethnic and racial health disparities. Through its extensive affiliation network involving five medical centers in the Bronx, Manhattan and Long Island - which includes Montefiore Medical Center, The University Hospital and Academic Medical Center for Einstein - the College of Medicine runs one of the largest post-graduate medical training programs in the United States, offering approximately 150 residency programs to more than 2,500 physicians in training. For more information, please visit www.einstein.yu.edu

Kimberly Newman | EurekAlert!
Further information:
http://www.einstein.yu.edu

More articles from Health and Medicine:

nachricht Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign

nachricht Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>