Antibiotic-resistant organisms such as MRSA can cause infections after surgery. Many studies have shown that MRSA nasal colonization increases the risk of developing SSI, and there has been an effort to conduct swab testing to isolate those patients and decontaminate or reduce the risk of MRSA SSI.
Researchers led by Harry T. Papaconstantinou, MD, chief of colorectal surgery at Scott and White Memorial Hospital, sought to determine the type of infection that might occur post-gastrointestinal (GI) surgery in someone who receives a nasal swab that tests positive for MRSA. The majority of organisms that cause SSIs after GI surgery usually occur within the body cavity operated on, but MRSA tends to colonize on the skin. Therefore, researchers expected to find that nasal colonization of MRSA wouldn't have an effect, as it is not an organism that is routinely found or colonized in the GI tract.
Of the 1,137 patients identified, 6 percent were MRSA positive, 15 percent were MSSA positive and 79 percent were negative. One hundred and one patients experienced SSI (9 percent), with the MRSA-positive group associated with a higher rate of SSI when compared to the negative and methicillin-sensitive Staphylococcus aureus (MSSA)-positive groups (14 percent versus 9 percent versus 4 percent, respectively).
Researchers also looked at other potential risk factors and found that the nasal swab result was not an indication of developing an SSI. "I don't think MRSA colonization necessarily increases risk for developing SSI, but I do think that MRSA colonization affects what type of organism is involved in SSI," said Dr. Papaconstantinou. He added that if you examine the organism present in SSIs, of the patients who tested positive for MRSA, 70 percent of their wound infections stemmed from MRSA.
Dr. Papaconstantinou said it is instructive to look at this research and consider what it takes to do a nasal swab test, to identify those with Staph aureus and differentiate between MRSA and MSSA, and then look at what it would cost to decolonize those patients. The next step for this research is to conduct surveillance and eradication of MRSA in bowel surgery.
Investigators examined all patients who had nasal swab tests at Scott and White Memorial Hospital between December 2007 and August 2009, and who had also undergone major gastrointestinal surgery (surgery of the esophagus, stomach, small bowel, colon and rectum, liver, gallbladder, pancreas, etc.) Patients had a nasal swab test to determine their MRSA colonization status within 24 to 48 hours after admission and were grouped into one of three categories: MRSA swab-positive, MSSA swab-positive, or those who had neither and were considered negative.
No pharmaceutical funding was provided for this study.
Dr. Papaconstantinou will present these data on Sunday, May 20 at 10:30 a.m. PT in Room 28ab at the San Diego Convention Center.
Amy Levey | EurekAlert!
Second cause of hidden hearing loss identified
20.02.2017 | Michigan Medicine - University of Michigan
Prospect for more effective treatment of nerve pain
20.02.2017 | Universität Zürich
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
20.02.2017 | Materials Sciences
20.02.2017 | Health and Medicine
20.02.2017 | Health and Medicine