Study findings have implications for patients' access to new treatments
A proportion of idiopathic pulmonary fibrosis (IPF) cases may be linked with asbestos exposure, according to the results of a new study. If confirmed, the findings would mean that current treatment strategies need to be altered as people with a history of asbestos exposure are not currently able to access new treatments for IPF.
The research, which was presented at the European Respiratory Society's International Congress today (09 September 2014), provided new mortality data for IPF, asbestosis and mesothelioma.
Asbestosis is the name given to the lung disease developed by people with a known history of exposure to asbestos. The symptoms and presentation of this disease can be identical to IPF; the only difference between the two diseases is whether a patient knows about their exposure to asbestos. People with asbestosis are not currently eligible for new treatments for IPF, despite the fact that these treatments work on curing an identical disease.
Researchers have suggested that a proportion of IPF may be due to unknown exposure to asbestos. They analysed mortality rates for IPF, asbestosis and mesothelioma across England and Wales. Data were obtained from the Office of National Statistics on the annual number of deaths due to IPF, mesothelioma and asbestos for the period 1974–2012, broken down by age, sex and region.
The analysis revealed national and regional correlations between the three diseases, which supports the theory that a proportion of IPF cases are due to unknown exposure to asbestos. If this asbestos exposure was known, it would be likely that these patients were diagnosed with asbestosis rather than IPF.
There were also high rates of IPF deaths in particular regions in the North West and South East of England, which has a history of shipyard work and therefore potential exposure to asbestos dust.
Lead researcher, Dr Carl Reynolds from Imperial College London, said: "The findings are consistent with the hypothesis that a proportion of IPF cases are likely to be caused by unknown exposure to asbestos. More research is needed in this area, particularly as patients known to have asbestos exposure are not currently considered to be candidates for new treatments for IPF and this may be inappropriate."
Lauren Anderson | Eurek Alert!
Penn studies find promise for innovations in liquid biopsies
30.03.2017 | University of Pennsylvania School of Medicine
'On-off switch' brings researchers a step closer to potential HIV vaccine
30.03.2017 | University of Nebraska-Lincoln
The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
30.03.2017 | Health and Medicine
30.03.2017 | Health and Medicine
30.03.2017 | Medical Engineering