Researchers at the Seaver Autism Center for Research and Treatment at Mount Sinai School of Medicine and Columbia University wanted to determine if oxytocin, popularly dubbed the “hormone of love,” could have widespread benefit in making us more understanding of others.
They conducted a randomized, double-blind, placebo-controlled, cross-over challenge, giving 27 healthy adult men oxytocin or a placebo delivered nasally. Participants then performed an empathic accuracy task in which they watched videos of people discussing emotional events from their life and rated how they thought the people in the videos were feeling.
Although all participants were healthy adults who did not have autism, the researchers looked at whether differences in social cognitive expertise affected response to oxytocin. Social competency was measured using the Autism Spectrum Quotient (AQ), a common self-report instrument that predicts social cognitive performance. Researchers hypothesized that oxytocin and AQ would interact to predict social cognitive performance. Results showed that oxytocin improved empathic accuracy, but only in those individuals who were less socially proficient.
“Oxytocin is widely believed to make all people more empathic and understanding of others,” said Jennifer Bartz, PhD, Assistant Professor, Psychiatry, Mount Sinai School of Medicine, and lead author of the study. “Our study contradicts that. Instead, oxytocin appears to be helpful only for those who are less socially proficient.”
More socially proficient participants performed well on the empathic accuracy task regardless of whether they were on oxytocin or placebo. By contrast, less socially proficient participants performed poorly on placebo but significantly better on oxytocin. In fact, on oxytocin, their empathic accuracy performance was identical to that of the socially proficient participants.
“Our data show that oxytocin selectively improves social cognition in people who are less socially proficient, but had little impact on more socially proficient individuals,” continued Dr. Bartz. “While more research is required, these results highlight the potential oxytocin holds for treating social deficits in people with disorders marked by deficits in social functioning like autism.”
Dr. Bartz and her colleagues also received a grant through the American Recovery and Reinvestment Act (ARRA), the federal government stimulus package, to continue her research on the impact of oxytocin beyond this study, specifically in adults with autism spectrum disorders.
About The Mount Sinai Medical Center
The Mount Sinai Medical Center encompasses both The Mount Sinai Hospital and Mount Sinai School of Medicine. Established in 1968, Mount Sinai School of Medicine is one of few medical schools embedded in a hospital in the United States. It has more than 3,400 faculty in 32 departments and 15 institutes, and ranks among the top 20 medical schools both in National Institute of Health funding and by U.S. News & World Report. The school received the 2009 Spencer Foreman Award for Outstanding Community Service from the Association of American Medical Colleges.
The Mount Sinai Hospital, founded in 1852, is a 1,171-bed tertiary- and quaternary-care teaching facility and one of the nation’s oldest, largest and most-respected voluntary hospitals. In 2009, U.S. News & World Report ranked The Mount Sinai Hospital among the nation’s top 20 hospitals based on reputation, patient safety, and other patient-care factors. Nearly 60,000 people were treated at Mount Sinai as inpatients last year, and approximately 530,000 outpatient visits took place.
For more information, visit www.mountsinai.org. Follow us on Twitter @mountsinainyc.
Mount Sinai Press Office | Newswise Science News
Penn studies find promise for innovations in liquid biopsies
30.03.2017 | University of Pennsylvania School of Medicine
'On-off switch' brings researchers a step closer to potential HIV vaccine
30.03.2017 | University of Nebraska-Lincoln
The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
30.03.2017 | Health and Medicine
30.03.2017 | Health and Medicine
30.03.2017 | Medical Engineering