A positive association between hypertension and depression has been reported in some inquiries but not in others, and the relationship was limited to individuals with diastolic blood pressure (DBP) in some studies.
Methodological difficulties are observed in previous research: some studies are based on self-reported hypertension, adjustment for potential confounders is not systematic and the use of a standardized psychiatric diagnosis is not common. This study tests the hypothesis of a positive association between hypertension and depression, and tries to circumvent the described methodological difficulties.
A large, stratified random sample of individuals from the census list aged 55 and over was selected. An epidemiological screening design was implemented, and standardized Spanish versions of assessment instruments were used, including the Geriatric Mental State (GMS), its computerized diagnostic program, AGECAT, and the History and Aetiology Schedule. The history of medical diseases was documented by means of the Risk Factor Questionnaire designed by the EURODEM Workgroup. The assessment of blood pressure followed World Health Organization standards, modified by the European Society of Hypertension, and Joint National Committee Seventh Report criteria were used for the diagnosis of hypertension. The specific hypothesis of the association of hypertension with depression was tested by means of logistic regression (LR) analysis.
At the end of the investigation, hypertension was documented in 2,523 individuals (61.0%; 41.7% were stage 1 and 19.3% were stage 2 hypertensives), and 314 of them (12.4%) were depressed. Results of LR analysis show, in the unadjusted model, that OR for depression was significantly higher in stage 2 hypertension (OR = 1.46, 95% CI = 1.12–1.90).
The results support the hypothesis that depression is secondary, since the association was found with moderate/severe hypertension (stage 2), but not with mild hypertension (stage 1). Prospective, sound longitudinal research is now needed to confirm the potential of hypertension at baseline to increase the risk for incident depression.
A. Lobo-Escolar, MD | alfa
'Exciting' discovery on path to develop new type of vaccine to treat global viruses
18.09.2017 | University of Southampton
A new approach to high insulin levels
18.09.2017 | Schweizerischer Nationalfonds SNF
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems Holding GmbH about commercial use of a multi-well tissue plate for automated and reliable tissue engineering & drug testing.
MBM ScienceBridge GmbH successfully negotiated a license agreement between University Medical Center Göttingen (UMG) and the biotech company Tissue Systems...
Pathogenic bacteria are becoming resistant to common antibiotics to an ever increasing degree. One of the most difficult germs is Pseudomonas aeruginosa, a...
Scientists from the MPI for Chemical Energy Conversion report in the first issue of the new journal JOULE.
Cell Press has just released the first issue of Joule, a new journal dedicated to sustainable energy research. In this issue James Birrell, Olaf Rüdiger,...
19.09.2017 | Event News
12.09.2017 | Event News
06.09.2017 | Event News
19.09.2017 | Event News
19.09.2017 | Physics and Astronomy
19.09.2017 | Power and Electrical Engineering