A positive association between hypertension and depression has been reported in some inquiries but not in others, and the relationship was limited to individuals with diastolic blood pressure (DBP) in some studies.
Methodological difficulties are observed in previous research: some studies are based on self-reported hypertension, adjustment for potential confounders is not systematic and the use of a standardized psychiatric diagnosis is not common. This study tests the hypothesis of a positive association between hypertension and depression, and tries to circumvent the described methodological difficulties.
A large, stratified random sample of individuals from the census list aged 55 and over was selected. An epidemiological screening design was implemented, and standardized Spanish versions of assessment instruments were used, including the Geriatric Mental State (GMS), its computerized diagnostic program, AGECAT, and the History and Aetiology Schedule. The history of medical diseases was documented by means of the Risk Factor Questionnaire designed by the EURODEM Workgroup. The assessment of blood pressure followed World Health Organization standards, modified by the European Society of Hypertension, and Joint National Committee Seventh Report criteria were used for the diagnosis of hypertension. The specific hypothesis of the association of hypertension with depression was tested by means of logistic regression (LR) analysis.
At the end of the investigation, hypertension was documented in 2,523 individuals (61.0%; 41.7% were stage 1 and 19.3% were stage 2 hypertensives), and 314 of them (12.4%) were depressed. Results of LR analysis show, in the unadjusted model, that OR for depression was significantly higher in stage 2 hypertension (OR = 1.46, 95% CI = 1.12–1.90).
The results support the hypothesis that depression is secondary, since the association was found with moderate/severe hypertension (stage 2), but not with mild hypertension (stage 1). Prospective, sound longitudinal research is now needed to confirm the potential of hypertension at baseline to increase the risk for incident depression.
A. Lobo-Escolar, MD | alfa
A promising target for kidney fibrosis
21.04.2017 | Brigham and Women's Hospital
Stem cell transplants: activating signal paths may protect from graft-versus-host disease
20.04.2017 | Technische Universität München
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
20.04.2017 | Event News
18.04.2017 | Event News
03.04.2017 | Event News
24.04.2017 | Life Sciences
24.04.2017 | Earth Sciences
24.04.2017 | Machine Engineering