Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Helicobacter pylori infection linked to decreased iron levels in otherwise healthy children

08.03.2011
Children without previous iron deficiencies or anemia who remained infected with Helicobacter pylori (H. pylori) had significantly lower levels of iron compared to children who had the infection eradicated, according to researchers at The University of Texas Health Science Center at Houston (UTHealth).

“Half of the world’s population is infected with H. pylori and most of the individuals are asymptomatically infected, according to several surveys,” said Victor Cardenas, M.D., Ph.D., lead investigator of the study and associate professor of epidemiology at The University of Texas School of Public Health El Paso Regional Campus, part of UTHealth.

“What we learned in this study is not only does H. pylori cause iron deficiency anemia and iron-deficiency, but that even among children who do not have these conditions, their levels of iron are lower than otherwise healthy children.” The research is published in the March issue of the Journal of Pediatric Gastroenterology and Nutrition.

Researchers investigated the link between H. pylori infection and iron levels in non-iron-deficient preschool and school age children in El Paso and found the infection causes a decrease in the levels of iron in children who do not have anemia or an iron deficiency. The bacterium H. pylori infects the lining of the stomach resulting in chronic swelling of tissue, a condition known as gastritis. H. pylori is also a major cause of peptic ulcer disease and the cause of most cancers of the stomach, according to the World Health Organization.

“Iron is an essential nutrient which supports several body functions and exists in small amounts in the body, but it is also required by bacteria such as H. pylori,” said Cardenas. “The infection decreases the body’s natural progression of making iron.” According to Cardenas, this is the first study conducted in the contiguous U.S. to examine the role of the infection on the levels of iron levels in asymptomatic children.

Over time markers of iron stored in the body increased in children no longer infected. However, children who remained infected lagged in levels of one marker, serum ferritin, at their six month follow-up. The protein serum ferritin measures the amount of iron stored in your body, according to the National Institute of Health.

“Previous research has shown that iron levels correlate with several body functions including brain activity and have well documented long-term health consequences such as increased morbidity and mortality and loss of productivity,” said Cardenas. “There is a need to research the long-term consequences of asymptomatic H. pylori infections in those without an iron deficiency because the effect we found could be present among those with normal iron levels.”

Cardenas and his team used a previously tested therapy, which consisted of one antacid plus one antibiotic for five days, followed by the antacid plus two antibiotics for another five days. While previous studies resulted in high rates of success in eradicating H. pylori, only half of the children given the active medications in Cardenas’ study had their infection eradicated, a disappointing result, he said.

Cardenas questions whether asymptomatic H. pylori infections have any significant health consequences. “We want to further investigate if there is a relation between variations of the bacteria strains and iron in adults,” said Cardenas.

Members of the research team led by Cardenas included investigators from Baylor College of Medicine, The University of North Texas, The University of Texas at El Paso and Texas Tech University Paul L. Foster School of Medicine. The research was funded by the Thrasher Research Fund.

Jade Waddy
Media Hotline: 713-500-3030

Jade Waddy | EurekAlert!
Further information:
http://www.uth.tmc.edu

More articles from Health and Medicine:

nachricht World first: Massive thrombosis removed during early pregnancy
20.07.2017 | Universitätsspital Bern

nachricht Therapy of preterm birth in sight?
19.07.2017 | Universitätsspital Bern

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

Im Focus: On the way to a biological alternative

A bacterial enzyme enables reactions that open up alternatives to key industrial chemical processes

The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....

Im Focus: The 1 trillion tonne iceberg

Larsen C Ice Shelf rift finally breaks through

A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...

Im Focus: Laser-cooled ions contribute to better understanding of friction

Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision

Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

Leipzig HTP-Forum discusses "hydrothermal processes" as a key technology for a biobased economy

12.07.2017 | Event News

 
Latest News

Researchers create new technique for manipulating polarization of terahertz radiation

20.07.2017 | Information Technology

High-tech sensing illuminates concrete stress testing

20.07.2017 | Materials Sciences

First direct observation and measurement of ultra-fast moving vortices in superconductors

20.07.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>