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Give Dirty Mouths a Brush

Toothpaste with Triclosan/Copolymer Kills Harmful Germs

The human mouth is home to an estimated 800 to 1,000 different kinds of bacteria. The warm and moist environment, along with hard tooth surfaces and soft tissues, prove to be optimal factors in boosting germ growth. Many of these bacteria are harmful and can form a film on teeth called “dental plaque,” which causes cavities, gingivitis and eventually more severe kinds of gum disease.

Toothpaste that contains triclosan/copolymer is better than regular fluoride toothpastes at killing the kinds of bacteria that live in people’s mouths, according to a study published in the January/February 2010 issue of General Dentistry, the peer-reviewed clinical journal of the Academy of General Dentistry (AGD).

“Manufacturers add specific agents to toothpastes to provide added benefits to consumers,” said Joseph J. Zambon, DDS, PhD, one of the study’s authors and a distinguished teaching professor at the University at Buffalo School of Dental Medicine. “The best known agent is fluoride, which was added to toothpaste to prevent cavities. Triclosan added to toothpaste has been shown in a number of clinical studies to inhibit plaque and gingivitis. The copolymer helps to keep triclosan in your mouth for a longer period of time, which boosts its ability to inhibit oral bacteria.”

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The triclosan/copolymer toothpaste and two fluoride toothpastes were tested on several different kinds of lab-grown bacteria that mimic germs found in the mouth. The tests were also done on bacteria taken from the mouths of human volunteers.

“Repetitive testing shows that toothpaste with triclosan/copolymer outperformed the fluoride-only toothpastes when it came to inhibiting the growth of bacteria,” Dr. Zambon said.

Along with brushing teeth twice a day, the AGD recommends the daily use of floss and a mouth rinse to reduce dental plaque and kill germs in the mouth.

"The importance of killing germs is that if you can keep your mouth relatively clean, you can minimize the likelihood of cavities and gum disease, as well as the unpleasantness of bad breath,” said Paul Bussman, DMD, FAGD, spokesperson for the AGD.

To learn more about good oral hygiene and health, visit

The Academy of General Dentistry (AGD) is a professional association of more than 35,000 general dentists dedicated to staying up to date in the profession through continuing education. Founded in 1952, the AGD has grown to become the second-largest dental association in the United States, and it is the only association that exclusively represents the needs and interest of general dentists. More than 772,000 persons are employed directly in the field of dentistry. A general dentist is the primary care provider for patients of all ages and is responsible for the diagnosis, treatment, management and overall coordination of services related to patients’ oral health needs. Learn more about AGD member dentists or find more information on dental health topics at

Contact: The AGD public relations department at 312.440.4346 or

Stefanie Schroeder | EurekAlert!
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