A next generation genome sequencer has been received in the newly launched Center for Translational Oncology Mainz and Immunology (TrOn) in Mainz. With the Illumina HiSeq 2000 instrument, the genetic material of cells can be completely decoded within a few days.
"The performance of TrOn as an innovation center and hub of the CI3 regional network of science and business is strengthened by this technology. This is therefore another important step to make Mainz a globally competitive center for personalized medicine," says Univ.-Prof. Dr. Ugur Sahin, director of TrOn. “The new technology allows us to examine the genetic information in tumor and immune cells quickly and inexpensively in order to gain a better understanding of the interplay of cancer treatment and immune system. This is necessary to develop customized therapies for individual patients."
"The new instrument is eight times more powerful than previous methods," says Dr. John Castle, head of Bioinformatics/Genomics at TrOn. "This represents not only a significant reduction of time and costs, but also more information that must be analyzed. For this, we are well positioned by our cooperation with the University of Mainz Center for High Performance Computing (ZDV)."
Understanding the characteristics of individual cancer patients is the basis for a customized treatment and thus critical to a successful therapy. "Individualized" and targeted medicine offers a great promise to significantly improve cancer therapy, both decreasing the cost of health care and improving patient lives. The dramatically increased ability to decode genomes ushered in by this next era of DNA sequencing makes the vision possible.
University President Univ.-Prof. Dr. Georg Krausch, a member of the successful Mainz "City of Science 2011" team, commented: "This is one of the puzzle pieces which we want at our site: cutting-edge research to resolve major social challenges."Press contact
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The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
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21.04.2017 | Physics and Astronomy