Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Gender differences in experience of rheumatism

15.09.2008
Rheumatoid arthritis is often a more painful experience for women than it is for men, even though the visible symptoms are the same.

Scientists are now saying that doctors should take more account of these subjective differences when assessing the need for medication. This and other findings are being presented at a congress currently in progress on gender medicine arranged by Karolinska Institutet.

For reasons yet unknown, rheumatoid arthritis is roughly three times more common amongst women than men. Moreover, several studies also suggest that rheumatoid arthritis eventually impairs the life quality of female suffers more than it does that of male sufferers. Here, too, the underlying reasons are unclear, but scientists have speculated that the medicines used affect women and men differently.

Researchers at Karolinska Institutet are now to present a study that gives vital clues as to why the prognosis is gender-specific. They have shown that men who undergo standard therapy for rheumatism respond significantly better than women having the same treatment – both objectively, such as in the degree of swelling in the joints, and subjectively in terms of their own experience of the disease.

“Purely objectively, the drug had a somewhat better effect on the men than on the women,” says associate professor Ronald van Vollenhoven, who led the study. “But the greatest difference was of a subjective nature. The women in the study felt sicker even when their joints showed the same improvements.”

According to Dr van Vollenhoven, it is important to take into account subjective difference when judging the severity of the disease. If doctors only consider the physical symptoms, people with severe pain might be deprived of the most effective medicine, which, owing to high costs and the risk of side-effects, is only given to the worst sufferers.

In a follow-up analysis, scientists compared the degree of disease in men and women who had received ‘biological’ medicines, which are only given to people who are considered seriously ill. The results of their study showed that while women and men who had been put on a course of treatment were at the same level as regards the objective manifestations of the disease, women felt themselves to be sicker than the men.

“Women and men have been treated on equal terms from the perspective of the doctors, but it’s possible that no one has been aware of the fact that the pain can be worse for women than for men,” says Dr van Vollenhoven. “Since our objective is to reduce suffering, we should try to take more account of the subjective aspects of rheumatoid arthritis.”

Sabina Bossi | alfa
Further information:
http://ki.se

More articles from Health and Medicine:

nachricht How cancer metastasis happens: Researchers reveal a key mechanism
19.01.2018 | Weill Cornell Medicine

nachricht Researchers identify new way to unmask melanoma cells to the immune system
17.01.2018 | Duke University Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Artificial agent designs quantum experiments

On the way to an intelligent laboratory, physicists from Innsbruck and Vienna present an artificial agent that autonomously designs quantum experiments. In initial experiments, the system has independently (re)discovered experimental techniques that are nowadays standard in modern quantum optical laboratories. This shows how machines could play a more creative role in research in the future.

We carry smartphones in our pockets, the streets are dotted with semi-autonomous cars, but in the research laboratory experiments are still being designed by...

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Let the good tubes roll

19.01.2018 | Materials Sciences

How cancer metastasis happens: Researchers reveal a key mechanism

19.01.2018 | Health and Medicine

Meteoritic stardust unlocks timing of supernova dust formation

19.01.2018 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>