Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Fresh findings about chickenpox could lead to better blood tests

09.06.2010
Fresh understanding of the virus that causes chickenpox and shingles could lead to improved vaccines and diagnostic tests, a study suggests.

Scientists at the University of Edinburgh devised a technique to separate the virus into its constituent proteins and then print them on to a biochip, before incubating the chip with blood from people who had previously had the infection.

They were able to pinpoint which proteins in the virus triggered a reaction in the body's immune system, giving scientists clues about how best to design a vaccine or blood test.

Researchers say the results may help create a test that offers improved sensitivity and earlier detection of infection compared with conventional tests. It would also offer accurate results in cases which might previously have been ambiguous, such as in vaccinated patients or patients with a pre-existing complaint.

Presently there is no test to show if an individual has acquired immunity against the virus through vaccination or a previous infection, and therefore determine if they are at risk of chickenpox or a secondary infection, which causes shingles. Such a test could show whether an elderly person would benefit from a booster vaccine to prevent shingles.

Dr Colin Campbell of the University of Edinburgh, who led the research, said: "This study has allowed us to look in great detail at the virus which causes chickenpox and we now know enough to design a better blood test than those currently available. This could help protect people for whom the infection represents a serious risk, such as pregnant women and elderly people with weak immune systems."

The research, also involving Dr Juergen Haas of the University of Edinburgh, was a collaboration with Arizona State University and the Ludwig-Maximilians University of Munich. It was supported by EaStCHEM and published in Molecular Biosystems.

Catriona Kelly | EurekAlert!
Further information:
http://www.ed.ac.uk

Further reports about: blood test chickenpox immune system vaccines

More articles from Health and Medicine:

nachricht 'Living bandages': NUST MISIS scientists develop biocompatible anti-burn nanofibers
16.02.2018 | National University of Science and Technology MISIS

nachricht New process allows tailor-made malaria research
16.02.2018 | Eberhard Karls Universität Tübingen

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: In best circles: First integrated circuit from self-assembled polymer

For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.

In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...

Im Focus: Demonstration of a single molecule piezoelectric effect

Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale

Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...

Im Focus: Hybrid optics bring color imaging using ultrathin metalenses into focus

For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.

But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...

Im Focus: Stem cell divisions in the adult brain seen for the first time

Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.

The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...

Im Focus: Interference as a new method for cooling quantum devices

Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters

Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

2nd International Conference on High Temperature Shape Memory Alloys (HTSMAs)

15.02.2018 | Event News

Aachen DC Grid Summit 2018

13.02.2018 | Event News

How Global Climate Policy Can Learn from the Energy Transition

12.02.2018 | Event News

 
Latest News

'Lipid asymmetry' plays key role in activating immune cells

20.02.2018 | Life Sciences

MRI technique differentiates benign breast lesions from malignancies

20.02.2018 | Medical Engineering

Major discovery in controlling quantum states of single atoms

20.02.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>