Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Finicky Fat

30.08.2010
Ever wonder why men and women gain weight in different areas of the body? Researchers are coming close to understanding the vital sex differences in men and women concerning fat storage. In fact, research indicates that fat is genetically different in men and women.

A groundbreaking medical study from members of the SWHR-Isis Fund Network on Sex Differences and Metabolism sponsored by the Society for Women’s Health Research (SWHR), the nation’s leading advocate for the study of sex differences, uncovers new truths about fat deposition in male and female mice.

"Given the difference in gene expression profiles, a female fat tissue won't behave anything like a male fat tissue and vice versa," said Deborah Clegg, Ph.D., assistant professor of internal medicine at UT Southwestern Medical Center. "The notion that fat cells between males and females are alike is inconsistent with our findings."

Mice store their fat similar to humans in a sexually dimorphic pattern. Just like human males, male mice store their fat in the belly and midsection area while females store fat in their hips, thighs and buttocks. Fat around your central organs (also known as central adiposity) is the type that is most dangerous for subsequent development of chronic diseases.

Dr. Clegg, the senior author of the study appearing in the International Journal of Obesity, was surprised by the findings. “We found that out of about 40,000 mouse genes, only 138 are commonly found in both male and female fat cells,” said Dr. Clegg. “This was completely unexpected. We expected the exact opposite - that 138 would be different and the rest would be the same between the sexes.”

This news is especially helpful in determining the underlying causes of obesity-related diseases. Since men are more likely to carry extra weight around their bellies, they are at higher risk for numerous obesity-related diseases including diabetes and heart disease. Women, on the other hand, are usually protected from these disorders until menopause, when their ovarian hormone levels drop and fat storage tends to shift from their buttocks to their waists.

“The research being performed by Dr. Clegg and colleagues underscores the importance of understanding the differences in fat deposition in men and women,” said Viviana Simon, Ph.D., SWHR vice president of scientific affairs. “The ability to manipulate how and where in the body fat is deposited holds the promise of helping researchers develop strategies to prevent or delay the development of chronic conditions such as diabetes and cardiovascular disease.”

For more information on the Society for Women’s Health Research please contact Rachel Griffith at 202-496-5001 or Rachel@swhr.org.

The Society for Women’s Health Research (SWHR), a national non-profit organization based in Washington D.C., is widely recognized as the thought leader in women’s health research, particularly how sex differences impact health. SWHR’s mission is to improve the health of all women through advocacy, education and research. Visit SWHR’s website at swhr.org for more information.

Rachel Griffith | Newswise Science News
Further information:
http://www.swhr.org

Further reports about: SWHR chronic condition chronic disease fat cells fat tissue health services

More articles from Health and Medicine:

nachricht Researchers release the brakes on the immune system
18.10.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn

nachricht Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Terahertz spectroscopy goes nano

20.10.2017 | Information Technology

Strange but true: Turning a material upside down can sometimes make it softer

20.10.2017 | Materials Sciences

NRL clarifies valley polarization for electronic and optoelectronic technologies

20.10.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>