Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Finicky Fat

30.08.2010
Ever wonder why men and women gain weight in different areas of the body? Researchers are coming close to understanding the vital sex differences in men and women concerning fat storage. In fact, research indicates that fat is genetically different in men and women.

A groundbreaking medical study from members of the SWHR-Isis Fund Network on Sex Differences and Metabolism sponsored by the Society for Women’s Health Research (SWHR), the nation’s leading advocate for the study of sex differences, uncovers new truths about fat deposition in male and female mice.

"Given the difference in gene expression profiles, a female fat tissue won't behave anything like a male fat tissue and vice versa," said Deborah Clegg, Ph.D., assistant professor of internal medicine at UT Southwestern Medical Center. "The notion that fat cells between males and females are alike is inconsistent with our findings."

Mice store their fat similar to humans in a sexually dimorphic pattern. Just like human males, male mice store their fat in the belly and midsection area while females store fat in their hips, thighs and buttocks. Fat around your central organs (also known as central adiposity) is the type that is most dangerous for subsequent development of chronic diseases.

Dr. Clegg, the senior author of the study appearing in the International Journal of Obesity, was surprised by the findings. “We found that out of about 40,000 mouse genes, only 138 are commonly found in both male and female fat cells,” said Dr. Clegg. “This was completely unexpected. We expected the exact opposite - that 138 would be different and the rest would be the same between the sexes.”

This news is especially helpful in determining the underlying causes of obesity-related diseases. Since men are more likely to carry extra weight around their bellies, they are at higher risk for numerous obesity-related diseases including diabetes and heart disease. Women, on the other hand, are usually protected from these disorders until menopause, when their ovarian hormone levels drop and fat storage tends to shift from their buttocks to their waists.

“The research being performed by Dr. Clegg and colleagues underscores the importance of understanding the differences in fat deposition in men and women,” said Viviana Simon, Ph.D., SWHR vice president of scientific affairs. “The ability to manipulate how and where in the body fat is deposited holds the promise of helping researchers develop strategies to prevent or delay the development of chronic conditions such as diabetes and cardiovascular disease.”

For more information on the Society for Women’s Health Research please contact Rachel Griffith at 202-496-5001 or Rachel@swhr.org.

The Society for Women’s Health Research (SWHR), a national non-profit organization based in Washington D.C., is widely recognized as the thought leader in women’s health research, particularly how sex differences impact health. SWHR’s mission is to improve the health of all women through advocacy, education and research. Visit SWHR’s website at swhr.org for more information.

Rachel Griffith | Newswise Science News
Further information:
http://www.swhr.org

Further reports about: SWHR chronic condition chronic disease fat cells fat tissue health services

More articles from Health and Medicine:

nachricht Cholesterol-lowering drugs may fight infectious disease
22.08.2017 | Duke University

nachricht Once invincible superbug squashed by 'superteam' of antibiotics
22.08.2017 | University at Buffalo

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Fizzy soda water could be key to clean manufacture of flat wonder material: Graphene

Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.

As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...

Im Focus: Exotic quantum states made from light: Physicists create optical “wells” for a super-photon

Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.

Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...

Im Focus: Circular RNA linked to brain function

For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.

While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...

Im Focus: RAVAN CubeSat measures Earth's outgoing energy

An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.

The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...

Im Focus: Scientists shine new light on the “other high temperature superconductor”

A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.

Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Call for Papers – ICNFT 2018, 5th International Conference on New Forming Technology

16.08.2017 | Event News

Sustainability is the business model of tomorrow

04.08.2017 | Event News

Clash of Realities 2017: Registration now open. International Conference at TH Köln

26.07.2017 | Event News

 
Latest News

What the world's tiniest 'monster truck' reveals

23.08.2017 | Life Sciences

Treating arthritis with algae

23.08.2017 | Life Sciences

Witnessing turbulent motion in the atmosphere of a distant star

23.08.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>