Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Eyebrain Tracker to be used in clinical trial for Parkinson’s therapy

06.12.2011
EyeBrain’s eye-tracking device will be used to evaluate the effects of levodopa on patients’ motricity

EyeBrain, a company developing medical devices for the early diagnosis of neurological diseases, announces today that its EyeBrain Tracker device is being used in a clinical trial exploring the dyskinesia induced by treating patients suffering from idiopathic Parkinson’s disease with levodopa.

The endpoint of the trial is to find biomarkers for the late-onset complications of a treatment regime using levodopa (BIODYS). This compound, which is naturally transformed into dopamine in the brain, is one of the only drugs available for slowing the effects of Parkinson’s disease. However, over time, it induces dyskinesia in these patients, which takes the form of abnormal movements primarily affecting the face (tongue, lips, jaw) and extending as far as the arms and legs.

Altogether, 30 people will be enrolled on the trial. Half of them will be Parkinson’s sufferers who have been treated with levodopa and have developed dyskinesia, while the other half will consist of healthy subjects who will be used as a control group.

The trial is being sponsored and financed by Bordeaux University Hospital and was set up by professor Jean-François Tison, a neurologist attached to the CNRS Physiopathology of Parkinsonian syndromes unit at the University of Bordeaux Two (the Institute of Neurodegenerative Diseases, CNRS UMR 5293E, Bezard). The EyeBrain Tracker device is being funded under the joint 2007-2013 State-Region Plan (Aquitaine Regional Council and the FEDER fund).

“Patients suffering from idiopathic Parkinson’s disease will undergo an acute test as part of a pre-operational assessment for stimulating the deep recesses of the brain,” explained professor Tison. The motricity effects of the treatment will be evaluated by measuring the speed of eye movements with the help of the EyeBrain Tracker.

“We will see whether levodopa modifies the parameters of blinking in a way that is correlated with the improvement in motricity,” said professor Tison. “Using the EyeBrain Tracker enables us to measure the motricity effect through eye movements, since the blinking parameters are also linked to the patient’s general motricity. The patient’s response to this trial is also a predictor of their reaction to the neurosurgery that will follow.”

The EyeBrain Tracker, which is already used in the early diagnosis of Parkinsonian syndromes, such as progressive supra-nuclear paralysis (PSP), cortico-basal degeneration (CBD) and multiple systems atrophy (MSA), is thus continuing to broaden its fields of application. It is now playing an important role in clinical research into other neurological diseases, such as multiple sclerosis, and is a valuable aid in the early diagnosis and follow-up of these diseases.

“We are delighted to know that the EyeBrain Tracker is playing a part in a clinical trial targeting idiopathic Parkinson’s,” said the chairman of EyeBrain, Serge Kinkingnéhun. “This forms part of our goal of making the benefits of eye motricity available to a larger number of people suffering from neurological pathologies.”

Parkinson’s disease is the second most common neurodegenerative disease after Alzheimer’s. In western countries it affects 0.3 per cent of the general population. Its prevalence increases with age, reaching one per cent in the over-60s, and as much as four per cent in the over-80s. There are 100,000 sufferers in France and 8,000 new cases are diagnosed each year.

About EyeBrain
EyeBrain manufactures medical devices for the early diagnosis of neurological diseases. These devices are based on the movement of the eyes, and they make it possible to test specific regions of the brain by recording and analyzing eye movements using very sophisticated algorithms developed by the company. EyeBrain’s devices fill a gap in neurological diagnostics. For the first time, clinicians can rely on a simple set of eye movement parameters to differentiate between very similar syndromes, such as progressive supra-nuclear paralysis (PSP) and cortico-basal degeneration (CBD). The test is easy to carry out, non-invasive, and the results are available in less than 20 minutes for a small cost.

The Mobile EyeBrain Tracker (EBT) comes as a complete solution including headphones, a computer with two screens and stimulation and analysis software. It is already being used routinely in hospitals to help with the early characterization of Parkinsonian syndromes. Studies are also underway for the diagnosis of multiple sclerosis (MS).

The Mobile EBT is the only device of its kind in the world to have obtained CE marking. The company has ISO 9001 and ISO 13485 certification.

EyeBrain, which is based in the Paris suburb of Ivry-sur-Seine, was founded in 2008 and currently employs 15 people. It has raised funding of EUR 1.2 million from the CapDecisif and G1J venture capital funds and already generates revenues through the sale of the EyeBrain Tracker. It is engaged in collaborations with the French National Health and Medical Research Institute (INSERM), the French National Scientific Research Center (CNRS), Paris University Hospitals group, the University of Paris-Descartes and the French Brain and Spinal Cord Institute.

For further information about the company, go to: http://www.eye-brain.com
For further information about eye tracking, go to: http://www.eyebrainpedia.com

Lucie Nguyen | Andrew Lloyd & Associates
Further information:
http://www.eye-brain.com

More articles from Health and Medicine:

nachricht Spanish scientists create a 3-D bioprinter to print human skin
24.01.2017 | Carlos III University of Madrid

nachricht Tracking movement of immune cells identifies key first steps in inflammatory arthritis
23.01.2017 | Massachusetts General Hospital

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Scientists spin artificial silk from whey protein

X-ray study throws light on key process for production

A Swedish-German team of researchers has cleared up a key process for the artificial production of silk. With the help of the intense X-rays from DESY's...

Im Focus: Quantum optical sensor for the first time tested in space – with a laser system from Berlin

For the first time ever, a cloud of ultra-cold atoms has been successfully created in space on board of a sounding rocket. The MAIUS mission demonstrates that quantum optical sensors can be operated even in harsh environments like space – a prerequi-site for finding answers to the most challenging questions of fundamental physics and an important innovation driver for everyday applications.

According to Albert Einstein's Equivalence Principle, all bodies are accelerated at the same rate by the Earth's gravity, regardless of their properties. This...

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Breaking the optical bandwidth record of stable pulsed lasers

24.01.2017 | Physics and Astronomy

Choreographing the microRNA-target dance

24.01.2017 | Life Sciences

Spanish scientists create a 3-D bioprinter to print human skin

24.01.2017 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>