A December 2007 PubMed search of English-language epidemiologic studies and their citations regarding dioxin exposure and CVD mortality provided the basis for the systemic review. The authors, researchers at the Harvard School of Public Health and the U.S. Environmental Protection Agency, selected studies on original mortality data from all cases of CVD or IHD.
They excluded studies of leather, flavor, and fragrance workers, whose occupational exposures typically include not only dioxin but also cardiotoxic methylmercury, arsenic and xylene. Finally, they grouped the studies by their quality, according to two well-recognized criteria. The studies considered to be of the highest quality found consistent and significant dose-related associations with IHD mortality and more modest associations with all-CVD mortality.
Although a number of epidemiologic studies have examined the association of dioxin exposure with CVD morbidity or mortality, the authors found no published systematic reviews on this topic. This is possibly because dioxin epidemiology research has focused primarily on the association with various cancers.
The authors wrote that future studies in both animals and humans should assess whether cardiovascular effects are present at environmentally relevant doses of dioxin.
EHP editor-in-chief Hugh A. Tilson, PhD, said, “With cardiovascular disease a leading cause of death in many countries, the potential role of dioxin exposure as a preventable risk factor could be of substantial interest.”
Authors include Olivier Humblet, Eric Rimm, Murray A. Mittleman, Russ Hauser, and Linda Birnbaum.
The article is available free of charge at http://www.ehponline.org/members/2008/11579/11579.html.
EHP is published by the National Institute of Environmental Health Sciences (NIEHS), part of the U.S. Department of Health and Human Services. EHP is an Open Access journal. More information is available online at http://www.ehponline.org/. Brogan & Partners Convergence Marketing handles marketing and public relations for the publication, and is responsible for creation and distribution of this press release.
Julie Hayworth-Perman | Newswise Science News
Organ-on-a-chip mimics heart's biomechanical properties
23.02.2017 | Vanderbilt University
Researchers identify cause of hereditary skeletal muscle disorder
22.02.2017 | Klinikum der Universität München
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded after a glide flight with an Airbus A320 in ditching on the Hudson River. All 155 people on board were saved.
On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded...
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
27.02.2017 | Materials Sciences
27.02.2017 | Interdisciplinary Research
27.02.2017 | Life Sciences