Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the findings indicate that women can reduce their breast cancer risk by exercising and maintaining their weight.
While studies have shown that physical activity reduces breast cancer risk, many questions remain. For example, how often, how long and how intense does physical activity have to be to provide benefits? Also, do women with all body types experience a reduced risk when they exercise, and does exercise reduce the risk of all types of breast cancer?
To investigate, Lauren McCullough, a doctoral candidate at the UNC Gillings School of Global Public Health, and her colleagues looked for a link between recreational physical activity, done at different time points in life, and the risk of developing breast cancer.
The study included 1,504 women with breast cancer (233 noninvasive and 1,271 invasive) and 1,555 women without breast cancer who were 20 to 98 years old and were part of the Long Island Breast Cancer Study Project, an investigation of possible environmental causes of breast cancer.
Women who exercised either during their reproductive or postmenopausal years had a reduced risk of developing breast cancer. Women who exercised 10 to 19 hours per week experienced the greatest benefit with an approximate 30 percent reduced risk. Risk reductions were observed at all levels of intensity, and exercise seemed to reduce the risk of hormone receptor positive breast cancers, the most commonly diagnosed tumor type among American women.
"The observation of a reduced risk of breast cancer for women who engaged in exercise after menopause is particularly encouraging given the late age of onset for breast cancer," McCullough said.
When the researchers looked at the joint effects of physical activity, weight gain and body size, they found that even active women who gained a significant amount of weight – particularly after menopause – had an increased risk of developing breast cancer, indicating that weight gain can eliminate the beneficial effects of exercise on breast cancer risk.
Co-authors of the study from UNC include Patrick T. Bradshaw, Ph.D., research assistant professor of nutrition, and Marilie D. Gammon, Ph.D., epidemiology professor, both from the Gillings School of Global Public Health, and Rebecca J. Cleveland, Ph.D., from the School of Medicine.
Other authors are Sybil M. Eng, Ph.D., department of epidemiology, Columbia University; Susan L. Teitelbaum, Ph.D., department of community medicine and prevention, Mount Sinai School of Medicine; and Alfred I. Neugut, M.D., Ph.D., department of medicine, Columbia University.
Link to article online: "Fat or Fit: The Joint Effects of PA, Weight Gain and Body Size on Breast Cancer Risk," http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1097-0142
Gillings School of Global Public Health contact: Chris Perry, (919) 966-4555, email@example.com
Chris Perry | EurekAlert!
Penn studies find promise for innovations in liquid biopsies
30.03.2017 | University of Pennsylvania School of Medicine
'On-off switch' brings researchers a step closer to potential HIV vaccine
30.03.2017 | University of Nebraska-Lincoln
The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.
To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...
Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...
In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
20.03.2017 | Event News
14.03.2017 | Event News
07.03.2017 | Event News
30.03.2017 | Health and Medicine
30.03.2017 | Health and Medicine
30.03.2017 | Medical Engineering